SCHEMBL8031158

SCHEMBL8031158

CCC(CC)Nc1ccc(Br)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 6/20 0.49
▸ KMT2A Q03164 6/20 0.49
▸ MAPT P10636 6/20 0.49
▸ POLB P06746 4/20 0.49
▸ L3MBTL1 Q9Y468 3/20 0.49
▸ ALDH1A1 P00352 3/20 0.49
▸ HTT P42858 2/20 0.49
▸ BLM P54132 3/20 0.43
▸ NSD2 O96028 1/20 0.43
▸ RXFP1 Q9HBX9 1/20 0.43
▸ IDO1 P14902 1/20 0.42
▸ TERT O14746 6/20 0.39
▸ TOP2B Q02880 1/20 0.39
▸ RAB9A P51151 3/20 0.38
▸ MAPK1 P28482 3/20 0.38
▸ TDP1 Q9NUW8 3/20 0.38
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ PABPC1 P11940 2/20 0.38
▸ EGFR P00533 1/20 0.38
▸ NPC1 O15118 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8639276 0.87 MEN1 (0.47) MEN1KMT2AMAPTPOLBL3MBTL1
SCHEMBL9163040 0.81 MEN1 (0.53) MEN1KMT2AMAPTPOLBL3MBTL1
SCHEMBL8652890 0.81 MEN1 (0.45) MEN1KMT2AMAPTPOLBL3MBTL1
SCHEMBL8034804 0.80 MAPT (0.62) MEN1KMT2AMAPTPOLBL3MBTL1
SCHEMBL968385 0.79 MAPT (0.61) MEN1KMT2AMAPTPOLBL3MBTL1
SCHEMBL11380137 0.79 MEN1 (0.59) MEN1KMT2AMAPTPOLBL3MBTL1
SCHEMBL11172894 0.78 MEN1 (0.47) MEN1KMT2AMAPTPOLBL3MBTL1
SCHEMBL10728067 0.78 MAPT (0.59) MEN1KMT2AMAPTPOLBL3MBTL1
SCHEMBL9165451 0.77 TERT (0.56) MEN1KMT2AMAPTPOLBL3MBTL1
SCHEMBL11309654 0.77 MAPT (0.46) MEN1KMT2AMAPTPOLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0683436-B1 Liquid toners utilizing highly fluorinated solvents MINNESOTA MINING & MFG (US) 2000-03-22 — — EP disclosed
US-5663024-A Liquid toners with hydrocarbon solvents MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-02 — — US disclosed
US-5599886-A Liquid toners with hydrocarbon solvents MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-02-04 — — US disclosed
US-5530053-A ELECTROSTATIC TONERS COMPRISING POLYMERIC DYES CONTAINING FLUORINATED MACROMERS COMPLEXED WITH A METAL CHARGE CONTROLLER; ANTIAGGLOMERANTS; QUICK-DRYING; TRANSFERABILITY; NON-FLAMMABLE; ELECTROGRAPHY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-06-25 — — US disclosed
US-5530067-A GRAFT FLUOROPOLYMERIC DYES FOR USE ELECTROGRAPHIC PROCESS; HIGH SPEED DRYING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-06-25 — — US disclosed
US-5521271-A Liquid toners with hydrocarbon solvents MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-05-28 — — US disclosed
EP-0706095-A1 Liquid toners with hydrocarbon solvents MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-04-10 — — EP disclosed
EP-0683436-A1 Liquid toners utilizing highly fluorinated solvents MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-11-22 — — EP disclosed
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