Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13002681 | 0.98 | DAO (0.39) | DAOOPRM1OPRK1OPRL1MAOB | |
| SCHEMBL8095388 | 0.94 | DAO (0.37) | DAOOPRM1OPRK1OPRL1MAOB | |
| SCHEMBL8095395 | 0.94 | DAO (0.37) | DAOOPRM1OPRK1OPRL1MAOB | |
| SCHEMBL8903961 | 0.94 | DAO (0.37) | DAOOPRM1OPRK1OPRL1MAOB | |
| SCHEMBL13002727 | 0.94 | DAO (0.37) | DAOOPRM1OPRK1OPRL1MAOB | |
| SCHEMBL8748183 | 0.91 | CYP1A2 (0.37) | DAOMAOBHCRTR1HCRTR2MAOA | |
| SCHEMBL13636443 | 0.90 | DAO (0.37) | DAOOPRM1OPRK1OPRL1HCRTR1 | |
| SCHEMBL8747987 | 0.90 | DAO (0.36) | DAOOPRM1MAOBHCRTR1HCRTR2 | |
| SCHEMBL8748009 | 0.88 | DAO (0.35) | DAOOPRM1HCRTR1HCRTR2CYP2C9 | |
| SCHEMBL8748047 | 0.88 | DAO (0.35) | DAOOPRM1HCRTR1HCRTR2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013198-A | LIQUID CRYSTALLINE COMPOUNDS MODIFIED TO HAVE A TRIFLUOROMETHYLPHENYL GROUP OR TRIFLUOROMETHOXYPHENYL GROUP AS EXAMPLE OF KNOWN TERMINAL SUBSTITUENT; CHEMICAL STABILITY, HIGH VOLTAGE HOLDING RATIO, GOOD UV STABILITY | CHISSO CORPORATION (JP) | 2000-01-11 | — | — | US | disclosed |
| EP-0761799-A1 | Liquid crystalline compound substituted with fluorine containing group, liquid crystal composition, and liquid crystal display device | Chisso Corporation (JP) | 1997-03-12 | — | — | EP | disclosed |