SCHEMBL8747987

SCHEMBL8747987

CCCCCC1CCC(CCC2CCC(CCc3cc(F)c(C(F)(F)F)c(F)c3)CC2)CC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
CYP3A4 P08684 2/20 0.33
CYP2C8 P10632 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
S1PR3 Q99500 1/20 0.33
CYP1A2 P05177 2/20 0.33
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
HCRTR1 O43613 1/20 0.31
HCRTR2 O43614 1/20 0.31
CNR2 P34972 1/20 0.31
OPRM1 P35372 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8748009 0.99 DAO (0.35) DAOMEN1KMT2ACYP3A4CYP2C8
SCHEMBL8748047 0.99 DAO (0.35) DAOMEN1KMT2ACYP3A4CYP2C8
SCHEMBL8748183 0.96 CYP1A2 (0.37) DAOKMT2ACYP3A4CYP1A2HTR2A
SCHEMBL13636530 0.93 PTGS2 (0.38) DAOCYP3A4CYP2C8CYP2D6CYP2C9
SCHEMBL8031324 0.90 DAO (0.38) DAOCYP2C9HTR2AHTR2CHTR2B
SCHEMBL13002681 0.88 DAO (0.39) DAOMEN1KMT2ACYP2C9HCRTR1
SCHEMBL7729141 0.88 DAO (0.31) DAO
SCHEMBL7729145 0.88 DAO (0.31) DAO
SCHEMBL9763910 0.87 MEN1 (0.36) MEN1KMT2ACYP3A4CYP2C8CYP2D6
SCHEMBL9763903 0.87 MEN1 (0.36) MEN1KMT2ACYP3A4CYP2C8CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0761799-A1 Liquid crystalline compound substituted with fluorine containing group, liquid crystal composition, and liquid crystal display device Chisso Corporation (JP) 1997-03-12 EP disclosed