Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FABP2 | P12104 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137350 | 0.83 | CES1 (0.52) | CES2CES1POLBALOX15TSHR | |
| SCHEMBL3443593 | 0.83 | CES2 (0.52) | CES2CES1POLBALOX15TSHR | |
| SCHEMBL29035924 | 0.83 | CES1 (0.52) | CES2CES1POLBALOX15TSHR | |
| SCHEMBL3128827 | 0.81 | CES2 (0.50) | CES2CES1POLBALOX15TSHR | |
| SCHEMBL17187854 | 0.80 | CES2 (0.54) | CES2CES1POLBALOX15TSHR | |
| SCHEMBL198250 | 0.80 | CES2 (0.54) | CES2CES1POLBALOX15TSHR | |
| SCHEMBL17187850 | 0.80 | CES1 (0.60) | CES2CES1POLBALOX15TSHR | |
| SCHEMBL978677 | 0.80 | CES1 (0.60) | CES2CES1POLBALOX15TSHR | |
| SCHEMBL10405986 | 0.80 | CES2 (0.59) | CES2CES1POLBALOX15TSHR | |
| Hydrochloric Acid SCHEMBL317255 | 0.79 | CES2 (0.48) | CES2CES1POLBALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103667-A | Phenylpyrazole herbicides | NOVARTIS CORPORATION (US) | 2000-08-15 | — | — | US | disclosed |
| EP-0832070-A1 | NOVEL HERBICIDES | Novartis AG (CH) | 1998-04-01 | — | — | EP | disclosed |
| WO-1997000246-A1 | NOVEL HERBICIDES | NOVARTIS AG (CH) | 1997-01-03 | — | — | WO | disclosed |