SCHEMBL978677

SCHEMBL978677

O=C(c1ccc(Cl)cc1)C(F)(F)F

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 4/20 0.60
CES2 O00748 3/20 0.54
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
MLYCD O95822 7/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
LMNA P02545 2/20 0.47
MAPT P10636 2/20 0.47
MEN1 O00255 1/20 0.47
POLB P06746 1/20 0.47
HSP90AA1 P07900 1/20 0.47
HTT P42858 1/20 0.47
KMT2A Q03164 1/20 0.47
SRD5A2 P31213 1/20 0.46
GSK3B P49841 1/20 0.46
MAPK1 P28482 1/20 0.46
TRPV1 Q8NER1 1/20 0.46
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17187850 1.00 CES1 (0.60) CES1CES2ALOX15TSHRMLYCD
SCHEMBL19371250 0.98 CES1 (0.58) CES1CES2ALOX15TSHRMLYCD
SCHEMBL29137350 0.84 CES1 (0.52) CES1CES2ALOX15TSHRCA1
SCHEMBL29035924 0.84 CES1 (0.52) CES1CES2ALOX15TSHRCA1
SCHEMBL28356967 0.82 CES1 (0.50) CES1CES2ALOX15TSHRCA1
SCHEMBL7738850 0.82 CES1 (0.50) CES1CES2ALOX15TSHRCA1
SCHEMBL19390100 0.82 CES2 (0.50) CES1CES2ALOX15TSHRCA1
SCHEMBL7880210 0.81 CES1 (0.60) CES1MLYCDTRPV1ALDH1A1
SCHEMBL8031369 0.80 CES2 (0.48) CES1CES2ALOX15TSHRCA1
SCHEMBL10405986 0.80 CES2 (0.59) CES1CES2ALOX15TSHRCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 226 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581071-A1 METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2025-07-09 EP claimed
US-11937599-B2 Microencapsulated herbicides MONSANTO TECHNOLOGY LLC (US) 2024-03-26 US claimed
WO-2024046712-A1 METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2024-03-07 WO claimed
CN-117334974-A Polyfluoro side chain anion exchange membrane for direct ammonia fuel cell and preparation method thereof 中国科学院大连化学物理研究所 2024-01-02 CN claimed
CN-114950159-B Preparation method of aromatic polymer separation membrane based on super acid catalysis 南京工业大学 2023-06-06 CN claimed
CN-114950159-A Preparation method of aromatic polymer separation membrane based on super-acid catalysis preparation 南京工业大学 2022-08-30 CN claimed
EP-3917319-A1 MICROENCAPSULATED ACETAMIDE HERBICIDES Monsanto Technology LLC (US) 2021-12-08 EP claimed
CN-113573584-A Microencapsulated acetamide herbicides 孟山都技术有限公司 2021-10-29 CN claimed
US-11129381-B2 Microencapsulated herbicides MONSANTO TECHNOLOGY LLC (US) 2021-09-28 US claimed
WO-2020160223-A1 MICROENCAPSULATED ACETAMIDE HERBICIDES MONSANTO TECHNOLOGY LLC (US) 2020-08-06 WO claimed
US-20200236928-A1 MICROENCAPSULATED ACETAMIDE HERBICIDES MONSANTO TECHNOLOGY LLC (US) 2020-07-30 US claimed
US-20200163331-A1 MICROENCAPSULATED HERBICIDES MONSANTO TECHNOLOGY LLC (US) 2020-05-28 US claimed
CN-106432171-B The preparation method of trifluoromethyl functionalization 1,3- dioxolane 石河子大学 2019-02-26 CN claimed
EP-3222712-A1 ALCOHOL DEHYDROGENASE FROM PICHIA PASTORIS AND USE THEREOF Universität zu Köln (DE) 2017-09-27 EP claimed
CN-106432171-A Method for preparing trifluoromethyl functionalized 1,3-dioxolane 石河子大学 2017-02-22 CN claimed
EP-4716679-A2 AGRICULTURAL COMPOSITION COMPRISING SURFACTANT(S) AND METHOD OF USE THEREOF Hercules LLC (US) 2026-04-01 EP disclosed
EP-4704575-A2 HYDROPHOBIC AND HYDROPHILIC MODIFIED MALEATED NATURAL OILS, SALTS AND ITS AGRICULTURAL COMPOSITIONS AND METHODS OF USE ISP Investments LLC (US) 2026-03-11 EP disclosed
US-4616027-A Antifungal 1-aryl-1-fluoroalkyl-2-(1H-1,2,4-triazol-1-yl)ethanols PFIZER INC. (US) 1986-10-07 US disclosed
US-4518604-A Antifungal 1-aryl-2-(1H-1,2,4-triazol-1yl)-1-perfluoroalkylethyl halides PFIZER INC. (US) 1985-05-21 US disclosed
EP-0110570-A2 Triazole antifungal agents Pfizer Limited (GB) 1984-06-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200163331-A1 MICROENCAPSULATED HERBICIDES HACL2, ACACB, HDHD5 CES1 510/4885CES2 53/4885ALOX15 1973/4885
US-11129381-B2 Microencapsulated herbicides HACL2, ACACB, HDHD5 CES1 510/4885CES2 53/4885ALOX15 1973/4885
US-11937599-B2 Microencapsulated herbicides HACL2, ACACB, HDHD5 CES1 510/4885CES2 53/4885ALOX15 1973/4885
US-20200236928-A1 MICROENCAPSULATED ACETAMIDE HERBICIDES HDHD5, HACL2, ACAA2 CES1 401/4885CES2 186/4885ALOX15 856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.