SCHEMBL8031491

SCHEMBL8031491

CCCCC(CC)C(=O)OOOC(C)(C)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.45
CA1 P00915 2/20 0.45
MAPK1 P28482 3/20 0.43
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 1/20 0.43
MAPT P10636 1/20 0.43
KMT2A Q03164 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
GAA P10253 1/20 0.43
XBP1 P17861 1/20 0.43
ATM Q13315 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TSHR P16473 1/20 0.40
CYP3A4 P08684 1/20 0.40
PRSS1 P07477 1/20 0.38
CTSG P08311 1/20 0.38
CTRB1 P17538 1/20 0.38
CMA1 P23946 1/20 0.38
CTSL P07711 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Ethylhexanoic Acid SCHEMBL28622409 0.83 MAPK1 (0.59) CA2CA1MAPK1ALDH1A1MEN1
Benzoyl Peroxide SCHEMBL29170939 0.81 ALDH1A1 (0.51) CA2CA1MAPK1ALDH1A1MEN1
SCHEMBL2806800 0.80 CA2 (0.53) CA2CA1MAPK1ALDH1A1MEN1
Bicarbonate SCHEMBL28738575 0.79 CA2 (0.54) CA2CA1MAPK1ALDH1A1MEN1
SCHEMBL29010174 0.78 ALDH1A1 (0.48) CA2CA1MAPK1ALDH1A1MEN1
SCHEMBL37317 0.78 CA2 (0.58) CA2CA1MAPK1ALDH1A1MEN1
SCHEMBL29517671 0.77 MAPK1 (0.44) MAPK1ALDH1A1MEN1KMT2ATSHR
SCHEMBL27702341 0.77 CA2 (0.49) CA2CA1MAPK1ALDH1A1MEN1
Acetic Acid SCHEMBL8858200 0.76 CA2 (0.51) CA2CA1MAPK1ALDH1A1MEN1
2-Ethylhexanoic Acid SCHEMBL2493057 0.76 CA2 (0.61) CA2CA1MAPK1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000068192-A2 PROCESS FOR THE PREPARATION OF (DI)ALKYLPEROXY ESTERS OF (DI)CARBOXYLIC ACIDS AKZO NOBEL N.V. (NL) 2000-11-16 WO disclosed
EP-0180789-B1 CROSS-LINKING OF STYRENE POLYMERS Luperox GmbH (DE) 1990-02-28 EP disclosed
US-4683248-A PEROXIDES AND UNSATURATED COMPOUNDS LUPEROX GMBH (DE) 1987-07-28 US disclosed
EP-0180789-A1 Cross-linking of styrene polymers Luperox GmbH (DE) 1986-05-14 EP disclosed