Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.46 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 2/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.34 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034431 | 0.91 | QPCT (0.46) | PPARDQPCTQPCTLMAOAP2RX3 | |
| SCHEMBL8030411 | 0.82 | MAOA (0.46) | MAOAKDM4EALDH1A1GPR84 | |
| SCHEMBL8014207 | 0.80 | MAOA (0.46) | MAOAGPR84 | |
| SCHEMBL1012836 | 0.79 | QPCT (0.49) | PPARDQPCTQPCTLMAOAP2RX3 | |
| SCHEMBL8024476 | 0.79 | MTOR (0.36) | PPARDQPCTQPCTLMAOAMTOR | |
| SCHEMBL1009219 | 0.74 | GRM5 (0.41) | PPARDQPCTQPCTLNPSR1KDM4E | |
| SCHEMBL1010622 | 0.74 | GRM5 (0.50) | PPARDALDH1A1HPGDKMT2A | |
| SCHEMBL3812015 | 0.74 | PPARD (0.41) | PPARDQPCTQPCTLHSD11B1NPSR1 | |
| SCHEMBL3814929 | 0.74 | PPARD (0.41) | PPARDQPCTQPCTLNPSR1KDM4E | |
| SCHEMBL1009272 | 0.72 | QPCT (0.49) | PPARDQPCTQPCTLMAOAP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095253-A1 | 6-HALO-PYRAZOLO[1, 5-A]PYRIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR (MGLUR) MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-08-06 | — | — | WO | disclosed |