Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 15/20 | 0.71 |
| ▸ | RARG | P13631 | 15/20 | 0.71 |
| ▸ | RARA | P10276 | 13/20 | 0.71 |
| ▸ | RXRA | P19793 | 10/20 | 0.54 |
| ▸ | RXRB | P28702 | 6/20 | 0.51 |
| ▸ | RXRG | P48443 | 4/20 | 0.51 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1616018 | 0.84 | RARB (1.00) | RARBRARGRARARXRARXRB | |
| SCHEMBL1615595 | 0.84 | RARB (1.00) | RARBRARGRARARXRARXRB | |
| SCHEMBL1615597 | 0.84 | RARB (1.00) | RARBRARGRARARXRARXRB | |
| SCHEMBL8032015 | 0.83 | RXRA (0.70) | RARBRARGRARARXRARXRB | |
| SCHEMBL8026153 | 0.76 | RARB (0.78) | RARBRARGRARARXRARXRB | |
| 4-Aminophenol SCHEMBL10842270 | 0.74 | RARB (0.79) | RARBRARGRARARXRARXRB | |
| 4-Aminophenol SCHEMBL10842256 | 0.74 | RARB (0.79) | RARBRARGRARARXRARXRB | |
| SCHEMBL9747847 | 0.74 | RARB (0.80) | RARBRARGRARARXRARXRB | |
| SCHEMBL1615305 | 0.74 | RARB (0.74) | RARBRARGRARARXRARXRB | |
| SCHEMBL1615307 | 0.74 | RARB (0.74) | RARBRARGRARARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000059861-A1 | SELECTIVE RETINOIC ACID ANALOGS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-10-12 | — | — | WO | claimed |