Alpha-Hydrazine Ornithine

Alpha-Hydrazine Ornithine

SCHEMBL8032273

NCCC[C@H](NN)C(=O)O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GNPAT O15228 3/20 0.55
FOLH1 Q04609 1/20 0.50
CPB2 Q96IY4 6/20 0.47
GSR P00390 1/20 0.45
RNPEP Q9H4A4 1/20 0.43
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
GGT1 P19440 1/20 0.40
SLC6A5 Q9Y345 1/20 0.39
GABRR1 P24046 3/20 0.38
GABRR3 A8MPY1 1/20 0.37
GABRP O00591 1/20 0.37
GABRD O14764 1/20 0.37
HDAC3 O15379 1/20 0.37
GABBR2 O75899 1/20 0.37
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37
THRB P10828 1/20 0.37
GABRA1 P14867 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alpha-Hydrazine Ornithine SCHEMBL5479325 1.00 GNPAT (0.55) GNPATFOLH1CPB2GSRRNPEP
SCHEMBL1272601 0.93 FOLH1 (0.58) GNPATFOLH1CPB2GSRRNPEP
SCHEMBL1272606 0.93 FOLH1 (0.58) GNPATFOLH1CPB2GSRRNPEP
SCHEMBL27043258 0.91 FOLH1 (0.56) GNPATFOLH1CPB2GSRRNPEP
SCHEMBL25140457 0.86
SCHEMBL29396372 0.84 FOLH1 (0.52) GNPATFOLH1CPB2GSRRNPEP
SCHEMBL1705338 0.83 FOLH1 (0.47) GNPATFOLH1CPB2GSRRNPEP
SCHEMBL1705339 0.83 FOLH1 (0.47) GNPATFOLH1CPB2GSRRNPEP
SCHEMBL472934 0.82 FOLH1 (0.50) GNPATFOLH1CPB2GSRRNPEP
SCHEMBL472937 0.82 FOLH1 (0.50) GNPATFOLH1CPB2GSRRNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107922928-A New transaminase and use its method to amino-compound deaminizating CJ第制糖株式会社 2018-04-17 CN disclosed
JP-2000219663-A DERIVATIVE OF N DELTA-SUBSTITUTED AMINO ORNITHINE AND ITS SALT TAIHO YAKUHIN KOGYO KK 2000-08-08 JP disclosed
JP-2000219663-A DERIVATIVE OF N DELTA-SUBSTITUTED AMINO ORNITHINE AND ITS SALT TAIHO YAKUHIN KOGYO KK 2000-08-08 JP disclosed