Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.51 |
| ▸ | ITGAV | P06756 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | YAP1 | P46937 | 3/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8346526 | 0.90 | KDM4E (0.48) | ITGB3ITGAVKDM4EPKMGPR119 | |
| SCHEMBL8019650 | 0.86 | ITGB3 (0.55) | ITGB3ITGAVKDM4EPKMGPR119 | |
| SCHEMBL8031246 | 0.86 | ITGB3 (0.55) | ITGB3ITGAVKDM4EPKMGPR119 | |
| SCHEMBL13074862 | 0.82 | ITGB3 (0.52) | ITGB3ITGAVKDM4EPKMGPR119 | |
| SCHEMBL8345100 | 0.79 | KDM4E (0.55) | KDM4EPKMGPR119NPC1ALDH1A1 | |
| SCHEMBL13855083 | 0.78 | ITGB3 (0.49) | ITGB3ITGAVKDM4EPKMGPR119 | |
| SCHEMBL7964098 | 0.78 | MAPT (0.51) | KDM4EPKMGPR119NPC1ALDH1A1 | |
| SCHEMBL8032542 | 0.77 | ITGB3 (0.47) | ITGB3ITGAVKDM4EPKMGPR119 | |
| SCHEMBL8019565 | 0.77 | ITGB3 (0.47) | ITGB3ITGAVKDM4EPKMGPR119 | |
| SCHEMBL3640283 | 0.76 | KDM4E (0.54) | KDM4EPKMGPR119YAP1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009058314-A1 | ENANTIOSELECTIVE PROCESS FOR PREPARING A SUBSTITUTED ALKANOIC ACID | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-05-07 | — | — | WO | disclosed |