Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 12/20 | 0.59 |
| ▸ | MMP1 | P03956 | 4/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032402 | 1.00 | MMP9 (0.59) | MMP9MMP1MMP2RAB9AALDH1A1 | |
| SCHEMBL8021143 | 0.78 | MMP9 (0.40) | MMP9RAB9AALDH1A1NPC1 | |
| SCHEMBL8021147 | 0.78 | MMP9 (0.40) | MMP9RAB9AALDH1A1NPC1 | |
| SCHEMBL7751613 | 0.76 | MMP9 (0.67) | MMP9MMP1MMP2RAB9AMMP12 | |
| SCHEMBL7751610 | 0.76 | MMP9 (0.67) | MMP9MMP1MMP2RAB9AMMP12 | |
| SCHEMBL8032374 | 0.75 | MMP9 (0.39) | MMP9RAB9AALDH1A1NPC1L3MBTL1 | |
| SCHEMBL8032378 | 0.75 | MMP9 (0.39) | MMP9RAB9AALDH1A1NPC1L3MBTL1 | |
| SCHEMBL8030531 | 0.74 | EPHX2 (0.39) | MMP9RAB9AALDH1A1NPC1 | |
| SCHEMBL8030528 | 0.74 | EPHX2 (0.39) | MMP9RAB9AALDH1A1NPC1 | |
| SCHEMBL8030511 | 0.73 | MMP9 (0.63) | MMP9MMP1MMP2MMP12DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127546-A | Process for the preparation of oxazoline compound | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 2000-10-03 | — | — | US | disclosed |