Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030531 | 1.00 | EPHX2 (0.39) | EPHX2RAB9ANPC1ALDH1A1MMP9 | |
| SCHEMBL8030521 | 0.87 | ACHE (0.38) | EPHX2RAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL8032378 | 0.83 | MMP9 (0.39) | RAB9ANPC1ALDH1A1MMP9MEN1 | |
| SCHEMBL8032374 | 0.83 | MMP9 (0.39) | RAB9ANPC1ALDH1A1MMP9MEN1 | |
| SCHEMBL8021147 | 0.82 | MMP9 (0.40) | EPHX2RAB9ANPC1ALDH1A1MMP9 | |
| SCHEMBL8021143 | 0.82 | MMP9 (0.40) | EPHX2RAB9ANPC1ALDH1A1MMP9 | |
| SCHEMBL8034356 | 0.77 | MMP9 (0.40) | RAB9ANPC1ALDH1A1MMP9 | |
| SCHEMBL8034360 | 0.77 | MMP9 (0.40) | RAB9ANPC1ALDH1A1MMP9 | |
| SCHEMBL8021205 | 0.76 | MMP9 (0.39) | RAB9ANPC1MMP9 | |
| SCHEMBL8021210 | 0.76 | MMP9 (0.39) | RAB9ANPC1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127546-A | Process for the preparation of oxazoline compound | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 2000-10-03 | — | — | US | disclosed |