Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
| ▸ | SELE | P16581 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8048051 | 0.83 | PTGS1 (0.32) | ALDH1A1MAPTPTGS1PTGS2RAB9A | |
| SCHEMBL8032529 | 0.83 | GAA (0.36) | ALDH1A1PKMICAM1SELEVCAM1 | |
| SCHEMBL8050229 | 0.79 | PTGS1 (0.30) | PTGS1PTGS2 | |
| SCHEMBL8041822 | 0.79 | ALDH1A1 (0.33) | ALDH1A1PTGS1PTGS2 | |
| SCHEMBL8033002 | 0.79 | PTGS1 (0.33) | ALDH1A1PTGS1PTGS2 | |
| SCHEMBL8044842 | 0.78 | FBP1 (0.47) | FBP1ALDH1A1NPSR1MAPK1PKM | |
| SCHEMBL8042342 | 0.78 | PTGS1 (0.33) | ALDH1A1MAPTPTGS1PTGS2RAB9A | |
| SCHEMBL8032336 | 0.77 | PTGS1 (0.32) | PTGS1PTGS2 | |
| SCHEMBL8046531 | 0.76 | PTGS1 (0.32) | PTGS1PTGS2 | |
| SCHEMBL8042604 | 0.76 | ALDH1A1 (0.35) | ALDH1A1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |