Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 12/20 | 0.62 |
| ▸ | ACE | P12821 | 12/20 | 0.62 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017966 | 0.94 | MME (0.63) | MMEACEPSEN1PSEN2APH1B | |
| SCHEMBL27463687 | 0.93 | MME (0.52) | MMEACEPSEN1PSEN2APH1B | |
| SCHEMBL8447804 | 0.90 | MME (0.64) | MMEACEPPARGPPARA | |
| SCHEMBL9007741 | 0.90 | MME (0.64) | MMEACEPPARGPPARA | |
| SCHEMBL8027420 | 0.90 | MME (0.77) | MMEACEPPARGPPARA | |
| SCHEMBL8027115 | 0.90 | MME (0.77) | MMEACEPSEN1PSEN2APH1B | |
| SCHEMBL8028717 | 0.87 | MME (0.67) | MMEACEPPARGPPARA | |
| SCHEMBL8448363 | 0.87 | MME (0.67) | MMEACEPPARGPPARA | |
| SCHEMBL8017233 | 0.87 | MME (0.68) | MMEACEPSEN1PSEN2APH1B | |
| SCHEMBL8027132 | 0.86 | MME (0.68) | MMEACEPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |