SCHEMBL9007741

SCHEMBL9007741

CCOC(=O)[C@H](Cc1ccc(-c2cccc3ccccc23)cc1)NC(=O)N(CC(C)C)CC(O)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MME P08473 12/20 0.64
ACE P12821 12/20 0.64
PPARG P37231 6/20 0.43
PPARA Q07869 6/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8447804 1.00 MME (0.64) MMEACEPPARGPPARA
SCHEMBL8027268 0.94 MME (0.65) MMEACEPPARGPPARA
SCHEMBL27464917 0.93 MME (0.54) MMEACEPPARGPPARA
SCHEMBL8027420 0.91 MME (0.77) MMEACEPPARGPPARA
SCHEMBL8032886 0.90 MME (0.62) MMEACEPPARGPPARA
SCHEMBL27463687 0.89 MME (0.52) MMEACEPPARGPPARA
SCHEMBL8026896 0.89 MME (0.80) MMEACE
SCHEMBL8026891 0.89 MME (0.80) MMEACE
SCHEMBL8448663 0.89 MME (0.80) MMEACE
SCHEMBL27441332 0.89 MME (0.57) MMEACEPPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0738711-A1 NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP SANTEN PHARMACEUTICAL CO., LTD. (JP) 1996-10-23 EP disclosed