SCHEMBL8032906

SCHEMBL8032906

OCC(CCl)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 5/20 0.42
GABBR2 O75899 2/20 0.41
GABBR1 Q9UBS5 2/20 0.41
TSHR P16473 2/20 0.40
CYP2D6 P10635 2/20 0.39
CYP1A2 P05177 1/20 0.39
PKM P14618 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
LMNA P02545 1/20 0.38
GSR P00390 1/20 0.37
HTR2A P28223 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
KDM4E B2RXH2 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
GAA P10253 1/20 0.36
SRC P12931 1/20 0.36
DPP4 P27487 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28576347 1.00 TRPA1 (0.42) TRPA1GABBR2GABBR1TSHRCYP2D6
SCHEMBL148756 0.85 TRPA1 (0.48) TRPA1GABBR2GABBR1TSHRCYP2D6
SCHEMBL5598365 0.85 TSHR (0.48) GABBR2GABBR1TSHRCYP2D6CYP1A2
SCHEMBL2010028 0.82 TRPA1 (0.46) TRPA1GABBR2GABBR1TSHRCYP2D6
SCHEMBL28884491 0.80 TRPA1 (0.50) TRPA1GABBR2GABBR1TSHRCYP2D6
SCHEMBL7612634 0.78 TRPA1 (0.43) TRPA1GABBR2GABBR1TSHRCYP2D6
SCHEMBL28431897 0.78 TRPA1 (0.43) TRPA1GABBR2GABBR1TSHRCYP2D6
Boric Acid SCHEMBL21356833 0.78 TRPA1 (0.43) TRPA1GABBR2GABBR1TSHRCYP2D6
SCHEMBL28156959 0.77 ALDH1A1 (0.40) CYP2D6SMN1; SMN2LMNAL3MBTL1GAA
SCHEMBL28156960 0.77 ALDH1A1 (0.40) CYP2D6SMN1; SMN2LMNAL3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115925673-B Preparation method of six-membered ring monothiocarbonate 浙江大学杭州国际科创中心 2024-06-11 CN claimed
CN-115925673-A Preparation method of six-membered ring monothiocarbonate 浙江大学杭州国际科创中心 2023-04-07 CN claimed
CN-115925673-B Preparation method of six-membered ring monothiocarbonate 浙江大学杭州国际科创中心 2024-06-11 CN disclosed
CN-118164947-A Preparation method of six-membered cyclic 1, 3-dioxane-2-ketone compound 中国石油化工股份有限公司 2024-06-11 CN disclosed
CN-115925673-A Preparation method of six-membered ring monothiocarbonate 浙江大学杭州国际科创中心 2023-04-07 CN disclosed
CN-107141188-B Asymmetric ring opening method and application of 3-substituted oxetane 香港科技大学深圳研究院 2021-05-28 CN disclosed
CN-107141188-A A kind of asymmetric open-loop method of 3- substitutions oxetanes and application 香港科技大学深圳研究院 2017-09-08 CN disclosed
US-6022822-A Organotin compound and catalyst for transesterification comprising the same RYOJI NOYORI (JP) 2000-02-08 US disclosed