SCHEMBL8032980

SCHEMBL8032980

O=COC1CC2C=CC1C2

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
EPHX2 P34913 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5071751 0.78 KDM4E (0.34) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL7029700 0.75 KDM4E (0.40) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL4402348 0.74 KDM4E (0.47) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL14449006 0.74 KDM4E (0.47) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL5718788 0.72 KDM4E (0.41) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL4967419 0.72 KDM4E (0.41) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL472764 0.72 KDM4E (0.41) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL4967632 0.72 KDM4E (0.41) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL5053685 0.72 EPHX2 (0.36) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL12256170 0.71 KDM4E (0.37) KDM4ELMNAALDH1A1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119505197-A Low-temperature-cured high-toughness polyester resin and preparation method and application thereof 擎天材料科技有限公司 2025-02-25 CN claimed
CN-115181397-B 3D printable high-strength high-toughness thermosetting resin composite material and preparation method and application thereof 南京林业大学 2023-11-21 CN claimed
CN-116284621-A Cycloolefin multiblock copolymer and preparation method and application thereof 南方科技大学 2023-06-23 CN claimed
CN-115181397-A High-strength high-toughness thermosetting resin composite material capable of being printed in 3D mode and preparation method and application thereof 南京林业大学 2022-10-14 CN claimed
CN-116284621-B Cycloolefin multiblock copolymer and preparation method and application thereof 南方科技大学 2026-05-19 CN disclosed
US-20250163418-A1 Brush polymer-oligonucleotide conjugates for the treatment of muscular dystrophy UNIV NORTHEASTERN (US) 2025-05-22 US disclosed
CN-119505197-A Low-temperature-cured high-toughness polyester resin and preparation method and application thereof 擎天材料科技有限公司 2025-02-25 CN disclosed
CN-117545511-A Thiol coupling with unsaturated phosphorus (V) compounds 柏林合作研究学会 2024-02-09 CN disclosed
CN-115181397-B 3D printable high-strength high-toughness thermosetting resin composite material and preparation method and application thereof 南京林业大学 2023-11-21 CN disclosed
CN-116284621-A Cycloolefin multiblock copolymer and preparation method and application thereof 南方科技大学 2023-06-23 CN disclosed
US-20230144534-A1 CLEAVABLE TETRAZINE USED IN BIO-ORTHOGONAL DRUG ACTIVATION TAGWORKS PHARMACEUTICALS B.V. (NL) 2023-05-11 US disclosed
CN-115884792-A Targeted poly (beta-amino esters) 艾夏卡法国有限公司 2023-03-31 CN disclosed
US-20190292310-A1 SYNTHESIS OF HIGH DENSITY MOLECULAR DNA BRUSHES VIA ORGANIC-PHASE RING-OPENING METATHESIS (CO)POLYMERIZATION NATIONAL SCIENCE FOUNDATION 2019-09-26 US disclosed
US-7714087-B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2010-05-11 US disclosed
EP-1734061-B1 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer and uses thereof MITSUI CHEMICALS INC (JP) 2010-04-07 EP disclosed
US-20090137757-A1 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof IMUTA JUNICHI 2009-05-28 US disclosed
US-7393907-B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2008-07-01 US disclosed
US-6048664-A Energy-sensitive resist material and a process for device fabrication using an energy-sensitive resist material LUCENT TECHNOLOGIES, INC. (US) 2000-04-11 US disclosed
US-4897473-A Homologation of carbonyloxy containing compounds UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) 1990-01-30 US disclosed
EP-0064287-A1 Homologation of carbonyloxy containing compounds and catalyst therefor UNION CARBIDE CORPORATION (US) 1982-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230144534-A1 CLEAVABLE TETRAZINE USED IN BIO-ORTHOGONAL DRUG ACTIVATION KIT, TPSB2, BTD KDM4E 2183/4885LMNA 1516/4885ALDH1A1 760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.