SCHEMBL8032985

SCHEMBL8032985

CCCCCC1NC(CCCCC)N(Cl)C1=O

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
HLCS P50747 1/20 0.30
CYP1A2 P05177 3/20 0.30
MMP1 P03956 1/20 0.30
MMP3 P08254 1/20 0.30
MMP9 P14780 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8029726 0.79 ALDH1A1 (0.33) ALDH1A1L3MBTL1HLCSCYP1A2MMP1
SCHEMBL5452034 0.66
SCHEMBL8029695 0.66 MMP1 (0.38) ALDH1A1MEN1KMT2ALMNAHTT
SCHEMBL8998181 0.65 ALDH1A1 (0.45) ALDH1A1MEN1KMT2ALMNAL3MBTL1
SCHEMBL5442521 0.65 ALDH1A1 (0.45) ALDH1A1MEN1KMT2AL3MBTL1HLCS
SCHEMBL10005090 0.65 ALDH1A1 (0.45) ALDH1A1MEN1KMT2AL3MBTL1HLCS
SCHEMBL10805173 0.64 ALDH1A1 (0.38) ALDH1A1MEN1KMT2ALMNAHTT
SCHEMBL4136352 0.64 TP53 (0.32) ALDH1A1MEN1KMT2ACYP1A2
SCHEMBL3622874 0.63 ALDH1A1 (0.44) ALDH1A1MEN1KMT2AL3MBTL1HLCS
SCHEMBL15298459 0.63 ALDH1A1 (0.48) ALDH1A1MEN1KMT2ALMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3072774-B2 2000-08-07 JP claimed
EP-0513239-B1 N,N'-DIHALOIMIDAZOLIDIN-4-ONES UNIV AUBURN (US) 1998-04-08 EP claimed
EP-0513239-A4 N,N'-DIHALOIMIDAZOLIDIN-4-ONES 1993-03-10 EP claimed
EP-0513239-A1 N,N'-DIHALOIMIDAZOLIDIN-4-ONES AUBURN UNIVERSITY (US) 1992-11-19 EP claimed
US-5126057-A Stabilizers against solar radiation AUBURN RESEARCH FOUNDATION (US) 1992-06-30 US claimed
WO-1991010623-A1 N,N'-DIHALOIMIDAZOLIDIN-4-ONES AUBURN UNIVERSITY (US) 1991-07-25 WO claimed