Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.54 |
| ▸ | ACE | P12821 | 6/20 | 0.54 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8522441 | 1.00 | MME (0.54) | MMEACEPPARGPPARAACACB | |
| SCHEMBL27464918 | 0.96 | MME (0.48) | MMEACEPPARGPPARAACACB | |
| SCHEMBL8451369 | 0.89 | MME (0.61) | MMEACEPPARGPPARA | |
| SCHEMBL8027308 | 0.89 | MME (0.61) | MMEACEPPARGPPARA | |
| SCHEMBL8028601 | 0.88 | MME (0.62) | MMEACEACACB | |
| SCHEMBL8452097 | 0.88 | MME (0.62) | MMEACEACACB | |
| SCHEMBL8028603 | 0.88 | MME (0.62) | MMEACEACACB | |
| SCHEMBL9007772 | 0.86 | MME (0.55) | MMEACE | |
| SCHEMBL8026907 | 0.86 | MME (0.55) | MMEACE | |
| SCHEMBL8452375 | 0.86 | MME (0.55) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |