Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.61 |
| ▸ | ACE | P12821 | 8/20 | 0.61 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027308 | 1.00 | MME (0.61) | MMEACEPPARGPPARANTSR1 | |
| SCHEMBL8522441 | 0.89 | MME (0.54) | MMEACEPPARGPPARA | |
| SCHEMBL8033023 | 0.89 | MME (0.54) | MMEACEPPARGPPARA | |
| SCHEMBL8448688 | 0.86 | MME (0.69) | MMEACE | |
| SCHEMBL8028819 | 0.86 | MME (0.69) | MMEACE | |
| SCHEMBL8028822 | 0.86 | MME (0.69) | MMEACE | |
| SCHEMBL27444746 | 0.86 | MME (0.56) | MMEACEPPARGPPARANTSR1 | |
| SCHEMBL27464918 | 0.85 | MME (0.48) | MMEACEPPARGPPARA | |
| SCHEMBL8027420 | 0.84 | MME (0.77) | MMEACEPPARGPPARANTSR1 | |
| SCHEMBL8030181 | 0.84 | MME (0.61) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891912-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| CN-1138321-A | 1, 3-dialkyl urea derivative with hydrocarbon group | SANTAN PHARMACEUTICAL CO LTD (JP) | 1996-12-18 | — | — | CN | disclosed |