Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MMP2 | P08253 | 6/20 | 0.47 |
| ▸ | MMP9 | P14780 | 6/20 | 0.47 |
| ▸ | MMP8 | P22894 | 4/20 | 0.45 |
| ▸ | MMP13 | P45452 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145409 | 0.86 | KMT2A (0.47) | LMNAMMP2MMP9MMP8MMP13 | |
| SCHEMBL918796 | 0.84 | LMNA (0.64) | LMNAMMP2MMP9MMP8MMP13 | |
| SCHEMBL4382583 | 0.82 | MMP9 (0.63) | LMNAMMP2MMP9MMP8MMP13 | |
| SCHEMBL4379822 | 0.82 | MMP9 (0.63) | LMNAMMP2MMP9MMP8MMP13 | |
| SCHEMBL712742 | 0.82 | MMP9 (0.63) | LMNAMMP2MMP9MMP8MMP13 | |
| SCHEMBL4390355 | 0.82 | MMP9 (0.63) | LMNAMMP2MMP9MMP8MMP13 | |
| SCHEMBL10580926 | 0.81 | CPT1A (0.51) | LMNAMMP2MMP9MMP8MMP13 | |
| SCHEMBL10583965 | 0.81 | CPT1A (0.51) | LMNAMMP2MMP9MMP8MMP13 | |
| SCHEMBL10582806 | 0.81 | CPT1A (0.51) | LMNAMMP2MMP9MMP8MMP13 | |
| SCHEMBL10582675 | 0.81 | CPT1A (0.51) | LMNAMMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000072848-A1 | COMPOSITION COMPRISING (±)-5-ETHYLDIHYDRO-5-(1-METHYLBUTYL)-2-THIOXO 4,6(1H,5H)-PYRIMIDINEDIONE DISSOLVED IN 2,5-DI-O-METHYL-1,4:3,6-DIANHYDRO-D-GLUCITOL | PATEL DINESH SHANTILAL (IN) | 2000-12-07 | — | — | WO | claimed |