Tetrahydrofuran

Tetrahydrofuran

SCHEMBL8033535

C1CCOC1.c1ccc2cc3c(ccc4cccc(OB(Oc5cccc6ccc7cc8ccccc8cc7c56)Oc5cccc6ccc7cc8ccccc8cc7c56)c43)cc2c1

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.35
ERBB2 P04626 1/20 0.35
FYN P06241 1/20 0.35
MAOA P21397 1/20 0.35
ACHE P22303 1/20 0.35
AHR P35869 1/20 0.35
PRKDC P78527 2/20 0.32
ALDH1A1 P00352 3/20 0.31
KDM4E B2RXH2 1/20 0.31
ALOX5 P09917 1/20 0.31
NQO1 P15559 1/20 0.30
APAF1 O14727 1/20 0.30
CDC25B P30305 1/20 0.30
CASP3 P42574 1/20 0.30
SENP8 Q96LD8 1/20 0.30
SENP7 Q9BQF6 1/20 0.30
HSD17B10 Q99714 2/20 0.30
HIF1A Q16665 1/20 0.30
CYP1B1 Q16678 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50100 0.88 CYP1A2 (0.43) CYP1A2ERBB2FYNMAOAACHE
Ammonia Solution, Strong SCHEMBL8665916 0.87 CYP1A2 (0.42) CYP1A2ERBB2FYNMAOAACHE
Trimethylammonium SCHEMBL5191404 0.82 CYP1A2 (0.39) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL16990771 0.79 CYP1A2 (0.36) CYP1A2ERBB2FYNMAOAACHE
Morpholine SCHEMBL11515192 0.78 APEX1 (0.32) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL7572908 0.78 HTR1B (0.36) CYP1A2ERBB2FYNMAOAACHE
Ammonia Solution, Strong SCHEMBL1010153 0.76 MCHR1 (0.35) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL49160 0.76 PRKDC (0.36) CYP1A2PRKDCALDH1A1KDM4EAPAF1
SCHEMBL19259375 0.76 CYP1A2 (0.41) CYP1A2ERBB2FYNMAOAACHE
Iodide SCHEMBL21808443 0.76 ERBB2 (0.33) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000069959-A2 POLYMER LAYERED INORGANIC NANOCOMPOSITES NATIONAL INSTITUTE OF STANDARDS & TECHNOLOGY (US) 2000-11-23 WO disclosed