Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TPH1 | P17752 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MME | P08473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8033729 | 0.99 | ALDH1A1 (0.55) | ALDH1A1TPH1MAPTMMELMNA | |
| SCHEMBL8017988 | 0.90 | ALDH1A1 (0.55) | ALDH1A1TPH1MAPTLMNANPSR1 | |
| Hydrochloric Acid SCHEMBL8017986 | 0.89 | ALDH1A1 (0.57) | ALDH1A1TPH1MAPTLMNANPSR1 | |
| SCHEMBL503583 | 0.82 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNANPSR1SMN1; SMN2 | |
| SCHEMBL22972798 | 0.82 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNANPSR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2787874 | 0.81 | ALDH1A1 (0.60) | ALDH1A1MAPTLMNANPSR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3813837 | 0.81 | ALDH1A1 (0.60) | ALDH1A1MAPTLMNANPSR1SMN1; SMN2 | |
| SCHEMBL27623048 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNANPSR1POLB | |
| SCHEMBL1376225 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNANPSR1POLB | |
| SCHEMBL7284208 | 0.78 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| US-5891912-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |