Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | NPC1 | O15118 | 9/20 | 0.60 |
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28114190 | 0.84 | PDPK1 (0.60) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL28116783 | 0.82 | NPC1 (0.72) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL14091304 | 0.81 | SMN1; SMN2 (0.54) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL31695045 | 0.79 | CHEK2 (0.55) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL227743 | 0.79 | NPC1 (0.78) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL12834409 | 0.78 | NT5E (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL12834042 | 0.78 | PDE5A (0.60) | NT5EFGFR1FLT1FGFR2AURKA | |
| SCHEMBL1902587 | 0.78 | MEN1 (1.00) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL20677815 | 0.77 | NPC1 (0.75) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL31677102 | 0.77 | NPC1 (0.66) | MEN1KMT2AALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106220611-A | The new preparation process of 2 (1H indole 3 base) 1H benzimidizole derivatives | 青岛科技大学 | 2016-12-14 | — | — | CN | disclosed |
| WO-2000078761-A1 | INDOLYL-BENZIMIDAZOLE ANTIBACTERIALS, AND METHODS OF USE THEREOF | SEPRACOR, INC. (US) | 2000-12-28 | — | — | WO | disclosed |