Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.72 |
| ▸ | RAB9A | P51151 | 9/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.72 |
| ▸ | HPGD | P15428 | 7/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.69 |
| ▸ | PKM | P14618 | 2/20 | 0.69 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.68 |
| ▸ | GLA | P06280 | 1/20 | 0.68 |
| ▸ | F7 | P08709 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL784353 | 0.94 | NPC1 (0.66) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL31677102 | 0.94 | NPC1 (0.66) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL29825055 | 0.94 | NPC1 (0.66) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| Benzene SCHEMBL29179821 | 0.93 | RAB9A (0.64) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL11857261 | 0.90 | NPC1 (0.76) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL27824963 | 0.90 | RAB9A (0.60) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL227743 | 0.90 | NPC1 (0.78) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL297468 | 0.86 | RAB9A (0.67) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL2494785 | 0.86 | NPC1 (0.61) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL27735312 | 0.85 | RAB9A (0.55) | NPC1RAB9AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187909-A | A kind of benzimidazolyl fluorescence chemical sensor for fluorion detection and preparation method thereof | 华南师范大学 | 2016-12-07 | — | — | CN | disclosed |