Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSH | P09668 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266149 | 0.92 | HIF1A (0.44) | HIF1AKCNN4CYP2C19TAAR1GRIN2D | |
| SCHEMBL111213 | 0.86 | ALDH1A1 (0.50) | HIF1AKCNN4CYP2C19TAAR1GRIN2D | |
| SCHEMBL11268748 | 0.85 | ALDH1A1 (0.48) | HIF1AKCNN4CYP2C19TAAR1GRIN2D | |
| SCHEMBL4590400 | 0.85 | MAPT (0.50) | HIF1AKCNN4CYP2C19TAAR1GRIN2D | |
| SCHEMBL5232906 | 0.84 | HIF1A (0.47) | HIF1AKCNN4CYP2C19MAPTKMT2A | |
| SCHEMBL24633608 | 0.83 | HIF1A (0.43) | HIF1AKCNN4CYP2C19TAAR1GRIN2D | |
| SCHEMBL18342544 | 0.83 | KCNN4 (0.43) | HIF1AKCNN4CYP2C19TAAR1GRIN2D | |
| SCHEMBL29109650 | 0.83 | GRIN2D (0.54) | HIF1AKCNN4CYP2C19TAAR1GRIN2D | |
| Hydrochloric Acid SCHEMBL3679217 | 0.83 | ALDH1A1 (0.47) | HIF1AKCNN4CYP2C19TAAR1GRIN2D | |
| SCHEMBL19820877 | 0.80 | GRIN2D (0.41) | HIF1AKCNN4CYP2C19TAAR1GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093792-A | COMPRISING FIRST COMONOMER UNITS DERIVED FROM LACTONES, LACTAMS, THIOLACTONES, OR NONFUNCTIONALIZED CYCLIC CARBONATES, AND SECOND COMONOMER UNITS DERIVED FROM FUNCTIONALIZED CYCLIC CARBONATES; MEDICAL USE | UNIVERSITY OF MASSACHUSETTS (US) | 2000-07-25 | — | — | US | disclosed |