Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 2/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | FNTA | P49354 | 2/20 | 0.36 |
| ▸ | FNTB | P49356 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049053 | 0.91 | GRIA2 (0.38) | GRIA2GRIA4PTGER4ARFNTA | |
| SCHEMBL8036061 | 0.89 | RARB (0.47) | GRIA2GRIA4PTGER4MMP2LTB4R2 | |
| SCHEMBL8036180 | 0.88 | RARB (0.43) | GRIA2GRIA4PTGER4MMP2LTB4R2 | |
| SCHEMBL7511079 | 0.87 | GRIA2 (0.47) | GRIA2GRIA4PTGER4ARFNTA | |
| SCHEMBL7511313 | 0.84 | GRIA2 (0.44) | GRIA2GRIA4PTGER4ARFNTA | |
| SCHEMBL4651806 | 0.82 | GRIA2 (0.43) | GRIA2GRIA4ARFNTAFNTB | |
| SCHEMBL7516259 | 0.81 | TSHR (0.46) | GRIA2GRIA4LTB4R2RARARARB | |
| SCHEMBL8048277 | 0.77 | GRIA2 (0.38) | GRIA2GRIA4PTGER4ARFNTA | |
| SCHEMBL8046378 | 0.76 | NOTUM (0.36) | GRIA2GRIA4RARARARBXDH | |
| SCHEMBL8047119 | 0.71 | RARA (0.36) | GRIA2GRIA4MMP2RARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805134-B1 | NOVEL LIQUID-CRYSTAL COMPOUNDS BEARING DIENYL MOIETY AND LIQUID-CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2000-08-30 | — | — | EP | disclosed |
| EP-0733692-B1 | Liquid crystalline compound, liquid crystal composition containing the same, and display device | CHISSO CORP (JP) | 2000-06-14 | — | — | EP | disclosed |
| US-5720899-A | Liquid crystalline compound, liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 1998-02-24 | — | — | US | disclosed |
| EP-0805134-A1 | NOVEL LIQUID-CRYSTAL COMPOUNDS BEARING DIENYL MOIETY AND LIQUID-CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-11-05 | — | — | EP | disclosed |