Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | PTPRF | P10586 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.34 |
| ▸ | CPB1 | P15086 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL3731973 | 0.94 | CYP2C19 (0.34) | TDP1CYP2C19SMN1; SMN2GPR84HDAC2 | |
| 1,4-Butanediol SCHEMBL3742477 | 0.91 | GPR84 (0.34) | TDP1CYP2C19SMN1; SMN2GPR84HDAC2 | |
| Di(Hydroxyethyl)Ether SCHEMBL3730783 | 0.89 | TSHR (0.44) | TDP1CYP2C19GPR84PTPRFPTPN2 | |
| Propylene Glycol SCHEMBL3728907 | 0.89 | TDP1 (0.34) | TDP1CYP2C19SMN1; SMN2GPR84PTPRF | |
| SCHEMBL11764465 | 0.88 | GPR84 (0.41) | GPR84PTPRFPTPN2PTPN1CPB2 | |
| SCHEMBL18141616 | 0.86 | GPR84 (0.44) | TDP1GPR84PTPN1SLC22A6 | |
| SCHEMBL4968928 | 0.84 | TDP1 (0.39) | TDP1SMN1; SMN2SLC22A6 | |
| SCHEMBL18139501 | 0.84 | GPR84 (0.47) | TDP1GPR84PTPN1SLC22A6 | |
| SCHEMBL18140164 | 0.84 | GPR84 (0.47) | TDP1GPR84PTPN1SLC22A6 | |
| SCHEMBL18139547 | 0.84 | GPR84 (0.47) | TDP1GPR84PTPN1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0989990-A1 | NON-SULFONATED CYANINE DYES FOR LABELING NUCLEOSIDES AND NUCLEOTIDES | Amersham Pharmacia Biotech Inc (US) | 2000-04-05 | — | — | EP | disclosed |
| WO-1998058942-A1 | NON-SULFONATED CYANINE DYES FOR LABELING NUCLEOSIDES AND NUCLEOTIDES | AMERSHAM PHARMACIA BIOTECH INC. (US) | 1998-12-30 | — | — | WO | disclosed |