Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8047253 | 0.91 | ACP1 (0.43) | RXRANR4A2NPSR1HPGDTSHR | |
| SCHEMBL8041741 | 0.89 | NPSR1 (0.42) | RXRANR4A2NPSR1HPGDTSHR | |
| SCHEMBL8038572 | 0.87 | NPSR1 (0.44) | RXRANR4A2NPSR1HPGDTSHR | |
| SCHEMBL8026809 | 0.86 | MDM2 (0.43) | RXRANR4A2NPSR1HPGDTSHR | |
| SCHEMBL4007857 | 0.84 | FABP3 (0.45) | RXRANR4A2NPSR1HPGDTSHR | |
| SCHEMBL8036843 | 0.83 | RXRA (0.45) | RXRANR4A2NPSR1HPGDTSHR | |
| SCHEMBL8037126 | 0.81 | PLA2G1B (0.41) | RXRANR4A2NPSR1HPGDTSHR | |
| SCHEMBL8040303 | 0.80 | NPSR1 (0.42) | NPSR1HPGDTSHRKDM4EMAPT | |
| SCHEMBL8023453 | 0.79 | RXRA (0.43) | RXRANR4A2NPSR1HPGDTSHR | |
| SCHEMBL8024898 | 0.79 | MAPT (0.40) | RXRANR4A2NPSR1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080242-A1 | SUBSTITUTED 4-AMINOPYRIMIDINE-5-CARBOXYLIC ACID AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |