Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | SELPLG | Q14242 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034522 | 0.86 | NPSR1 (0.47) | RXRANR4A2NPSR1HPGDTSHR | |
| SCHEMBL8034289 | 0.83 | RXRA (0.43) | RXRANR4A2NPSR1HPGDTSHR | |
| SCHEMBL4011470 | 0.81 | FABP3 (0.45) | RXRANR4A2NPSR1HPGDTSHR | |
| SCHEMBL8040520 | 0.81 | NPSR1 (0.43) | RXRANR4A2NPSR1HPGDTSHR | |
| SCHEMBL4008510 | 0.78 | FABP3 (0.43) | RXRANR4A2NPSR1HPGDTSHR | |
| SCHEMBL4008885 | 0.76 | FABP3 (0.41) | NPSR1HPGDFABP3FABP4FABP5 | |
| SCHEMBL4014246 | 0.76 | MEN1 (0.46) | RXRANR4A2NPSR1HPGDTSHR | |
| SCHEMBL8032359 | 0.76 | FABP3 (0.43) | RXRANR4A2NPSR1HPGDTSHR | |
| SCHEMBL8035080 | 0.75 | TSHR (0.47) | RXRANR4A2NPSR1HPGDTSHR | |
| SCHEMBL4015161 | 0.75 | ATM (0.54) | RXRANR4A2NPSR1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080242-A1 | SUBSTITUTED 4-AMINOPYRIMIDINE-5-CARBOXYLIC ACID AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |