Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10024806 | 1.00 | AKR1C3 (0.53) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL803238 | 0.94 | AKR1C3 (0.50) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL13703908 | 0.92 | AKR1C3 (0.58) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL23173084 | 0.92 | AKR1C3 (0.58) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL21373998 | 0.91 | PTGS2 (0.45) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL10018722 | 0.90 | AKR1C3 (0.54) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL14365640 | 0.90 | AKR1C3 (0.54) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL4567629 | 0.90 | PDE3B (0.48) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL10018704 | 0.90 | NISCH (0.46) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL10014184 | 0.90 | NISCH (0.46) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043781-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2024-07-23 | — | — | US | disclosed |
| US-11781069-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2023-10-10 | — | — | US | disclosed |
| US-11718791-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2023-08-08 | — | — | US | disclosed |
| US-11702597-B2 | Azo dye | MERCK PATENT GMBH (DE) | 2023-07-18 | — | — | US | disclosed |
| US-11685863-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2023-06-27 | — | — | US | disclosed |
| US-11667845-B2 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2023-06-06 | — | — | US | disclosed |
| US-11655417-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2023-05-23 | — | — | US | disclosed |
| WO-2020038861-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2020-02-27 | — | — | WO | disclosed |
| US-20180201837-A1 | Method of Reducing ODF Mura in Polymer Stabilised Liquid Crystal Displays | MERCK PATENT GMBH (DE) | 2018-07-19 | — | — | US | disclosed |
| US-20180195003-A1 | PROCESS FOR THE STABILISATION OF LIQUID CRYSTAL MEDIA | MERCK PATENT GMBH (DE) | 2018-07-12 | — | — | US | disclosed |
| US-20100188618-A1 | LIQUID-CRYSTAL DISPLAY | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2010-07-29 | — | — | US | disclosed |
| US-7731865-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2010-06-08 | — | — | US | disclosed |
| US-20090324853-A1 | LIQUID-CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2009-12-31 | — | — | US | disclosed |
| EP-2116522-A1 | PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING CF<SB>2</SB>O BONDING GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY | Chisso Corporation (JP) | 2009-11-11 | — | — | EP | disclosed |
| US-20090141215-A1 | POLYMERIZABLE COMPOUNDS | MERCK PATENT GESELLSCHAFT (DE) | 2009-06-04 | — | — | US | disclosed |
| US-20090103011-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GESELLSCHAFT (DE) | 2009-04-23 | — | — | US | disclosed |
| US-7462297-B2 | Chiral dopants having a laterally alkylated phenyl structural element | MERCK PATENT GMBH (DE) | 2008-12-09 | — | — | US | disclosed |
| US-20080090026-A1 | Liquid-crystal display | MERCK PATENT GMBH | 2008-04-17 | — | — | US | disclosed |
| US-7294368-B2 | Liquid crystal composition for use in bistable liquid crystal devices | MERCK PATENT GMBH (DE) | 2007-11-13 | — | — | US | disclosed |
| US-7258903-B2 | Fast switching liquid crystal compositions for use in bistable liquid crystal devices | MERCK PATENT GMBH (DE) | 2007-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718791-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | VCL, ILK, LCP1 | AKR1C3 4067/4885AKR1C2 4097/4885AKR1B10 4234/4885 |
| US-11667845-B2 | Liquid crystalline medium | NEFM, CCNI, MYT1 | AKR1C3 4108/4885AKR1C2 4449/4885AKR1B10 4312/4885 |
| US-11685863-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | LPXN, VCL, LCP1 | AKR1C3 3514/4885AKR1C2 3386/4885AKR1B10 3441/4885 |
| US-20080090026-A1 | Liquid-crystal display | KLK3, LPXN, BPHL | AKR1C3 3095/4885AKR1C2 2576/4885AKR1B10 2010/4885 |
| US-20090141215-A1 | POLYMERIZABLE COMPOUNDS | VCL, LCP1, LPXN | AKR1C3 3773/4885AKR1C2 3623/4885AKR1B10 3269/4885 |
| US-20100188618-A1 | LIQUID-CRYSTAL DISPLAY | KLK3, LPXN, PSAP | AKR1C3 3702/4885AKR1C2 3470/4885AKR1B10 3026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.