SCHEMBL8034307

SCHEMBL8034307

FC(F)(F)c1n[c]sc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8806177 0.69
SCHEMBL18938665 0.67
SCHEMBL2439830 0.67 GPR35 (0.33)
SCHEMBL9214541 0.67
SCHEMBL8807708 0.62
SCHEMBL2579554 0.62
SCHEMBL8806645 0.59 MEN1 (0.39)
SCHEMBL3067173 0.57 ENPP3 (0.33)
SCHEMBL6276128 0.57 ENPP3 (0.33)
SCHEMBL9220348 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0805795-B1 NOVEL AROMATIC AMIDES, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS PESTICIDES HOECHST SCHERING AGREVO SA (FR) 2000-08-23 EP claimed
US-20240108006-A1 PESTICIDALLY ACTIVE HETEROAROMATIC COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2024-04-04 US disclosed
WO-2024022910-A1 1-[1-[2-(PYRIMIDIN-4-YL)-1,2,4-TRIAZOL-3-YL]ETHYL]-3-[2,4-DICHLORO-5-PHENYL]UREA DERIVATIVES AND SIMILAR COMPOUNDS AS PESTICIDES SYNGENTA CROP PROTECTION AG (CH) 2024-02-01 WO disclosed
CN-117412961-A Pesticidally active heteroaromatic compounds 先正达农作物保护股份公司 2024-01-16 CN disclosed
EP-4281185-A2 PESTICIDALLY ACTIVE HETEROAROMATIC COMPOUNDS Syngenta Crop Protection AG (CH) 2023-11-29 EP disclosed
US-6159973-A Aromatic amides, their preparation process, the compositions containing them and their use as pesticides HOECHST SCHERING AGREVO S.A. (FR) 2000-12-12 US disclosed
US-6013837-A E.G.,4-(2-(3,4,5-TRICHLORO PHENYL) 1-FLUOROCYCLOPROPYL)-N-(2-METHYL PHENYL)BENZAMIDE; PARTICULAR USE AGAINST ARTHROPODS, HELMINTHS AND MOLLUSCS; INSECTICIDES; ACARICIDES; NEMATICIDES; PHOTOSTABILITY; NONTOXIC TO MAMMALS HOECHST MARION ROUSSEL (FR) 2000-01-11 US disclosed
EP-0476456-B1 Substituted 2-thiazolyl tetrazolium salt indicators BAYER AG (US) 1997-11-12 EP disclosed
EP-0476454-B1 Analytical method using tetrazolium salt indicators having a reflectance plateau BAYER AG (US) 1996-10-23 EP disclosed
US-5322680-A Chromogenic detector for medical diagnosis by forming formazan dyes chemical reduction MILES INC. (US) 1994-06-21 US disclosed
US-5126275-A Chromogenic reducing indicators for reducing substances such as NADH MILES INC. (US) 1992-06-30 US disclosed
EP-0476456-A2 Substituted 2-thiazolyl tetrazolium salt indicators Bayer Corporation (US) 1992-03-25 EP disclosed