Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | USP1 | O94782 | 1/20 | 0.37 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034360 | 1.00 | MMP9 (0.40) | MMP9USP1WDR48POLBPTGDR2 | |
| SCHEMBL8034368 | 0.85 | TSHR (0.40) | TSHR | |
| SCHEMBL8021210 | 0.81 | MMP9 (0.39) | MMP9USP1WDR48KDM4ENPC1 | |
| SCHEMBL8021205 | 0.81 | MMP9 (0.39) | MMP9USP1WDR48KDM4ENPC1 | |
| SCHEMBL8032366 | 0.81 | MMP9 (0.43) | MMP9USP1WDR48POLBNPC1 | |
| SCHEMBL8032370 | 0.81 | MMP9 (0.43) | MMP9USP1WDR48POLBNPC1 | |
| SCHEMBL8021153 | 0.79 | MMP9 (0.44) | MMP9USP1WDR48POLBNPC1 | |
| SCHEMBL8021154 | 0.79 | MMP9 (0.44) | MMP9USP1WDR48POLBNPC1 | |
| SCHEMBL8021184 | 0.78 | USP1 (0.44) | MMP9USP1WDR48POLBKDM4E | |
| SCHEMBL8021186 | 0.78 | USP1 (0.44) | MMP9USP1WDR48POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127546-A | Process for the preparation of oxazoline compound | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 2000-10-03 | — | — | US | disclosed |