Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 7/20 | 0.41 |
| ▸ | PREP | P48147 | 6/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034164 | 1.00 | FKBP1A (0.41) | FKBP1APREPCHRM2CHRM1CHRM3 | |
| SCHEMBL8034166 | 1.00 | FKBP1A (0.41) | FKBP1APREPCHRM2CHRM1CHRM3 | |
| SCHEMBL8034823 | 0.84 | FKBP1A (0.49) | FKBP1APREP | |
| SCHEMBL8051856 | 0.84 | FKBP1A (0.49) | FKBP1APREP | |
| SCHEMBL8043720 | 0.84 | FKBP1A (0.49) | FKBP1APREP | |
| SCHEMBL19075817 | 0.75 | PREP (0.43) | PREPCHRM2CHRM1CHRM3 | |
| SCHEMBL19075578 | 0.75 | PREP (0.43) | PREPCHRM2CHRM1CHRM3 | |
| SCHEMBL8046179 | 0.74 | FKBP1A (0.57) | FKBP1APREP | |
| SCHEMBL8046183 | 0.74 | FKBP1A (0.57) | FKBP1APREP | |
| SCHEMBL7252528 | 0.73 | FKBP1A (0.44) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121280-A | Azabicyclic rotomase inhibitors | PFIZER INC. (US) | 2000-09-19 | — | — | US | disclosed |
| EP-0947506-A1 | 2-Aza-bicyclo[2.2.1]heptane derivatives and their use as rotamase inhibitors | Pfizer Products Inc. (US) | 1999-10-06 | — | — | EP | disclosed |