Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 14/20 | 0.49 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034823 | 1.00 | FKBP1A (0.49) | FKBP1APREPMAPT | |
| SCHEMBL8051856 | 1.00 | FKBP1A (0.49) | FKBP1APREPMAPT | |
| SCHEMBL8034533 | 0.84 | FKBP1A (0.41) | FKBP1APREP | |
| SCHEMBL8034166 | 0.84 | FKBP1A (0.41) | FKBP1APREP | |
| SCHEMBL8034164 | 0.84 | FKBP1A (0.41) | FKBP1APREP | |
| SCHEMBL8046179 | 0.79 | FKBP1A (0.57) | FKBP1APREP | |
| SCHEMBL8046183 | 0.79 | FKBP1A (0.57) | FKBP1APREP | |
| SCHEMBL2097353 | 0.79 | PREP (0.61) | PREPMAPT | |
| SCHEMBL15934580 | 0.79 | PREP (0.61) | PREPMAPT | |
| SCHEMBL21966212 | 0.79 | PREP (0.40) | FKBP1APREPMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121280-A | Azabicyclic rotomase inhibitors | PFIZER INC. (US) | 2000-09-19 | — | — | US | disclosed |