SCHEMBL8034859

SCHEMBL8034859

CC(C)c1ccc(N(c2ccccc2)c2ccc(C=O)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.66
ALDH1A1 P00352 6/20 0.47
ALDH1A3 P47895 2/20 0.47
ALDH3A1 P30838 1/20 0.47
CYP2A6 P11509 2/20 0.46
CYP2A13 Q16696 1/20 0.46
CNR1 P21554 2/20 0.43
CNR2 P34972 2/20 0.43
KDM4E B2RXH2 2/20 0.42
MAPT P10636 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MAPK1 P28482 2/20 0.42
APP P05067 1/20 0.39
FAAH O00519 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3340608 0.93 TYR (0.76) TYRALDH1A1ALDH1A3ALDH3A1CYP2A6
SCHEMBL12292310 0.86 RELA (0.50) TYRALDH1A1KDM4EMAPTL3MBTL1
SCHEMBL18353270 0.86 RELA (0.50) TYRALDH1A1KDM4EMAPTL3MBTL1
Cuminaldehyde SCHEMBL4109069 0.85 TYR (0.83) TYRALDH1A1ALDH1A3CYP2A6KDM4E
SCHEMBL181026 0.85 ALDH1A1 (0.59) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL2199745 0.85 ALDH1A1 (0.59) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL28032989 0.85 ALDH1A1 (0.59) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL851178 0.85 ALDH1A1 (0.59) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL13649928 0.85 ALDH1A1 (0.59) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL1102464 0.85 ALDH1A1 (0.56) TYRALDH1A1CNR1CNR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6090514-A ELECTROPHOTOSENSITIVE MATERIAL COMPRISING CONDUCTIVE SUBSTRATE AND SINGLE PHOTOSENSITIVE LAYER CONTAINING STILBENE DERIVATIVE AS HOLE TRANSFERRING MATERIAL MITA INDUSTRIAL CO., LTD. (JP) 2000-07-18 US disclosed