Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038220 | 0.90 | PPIA (0.42) | ALDH1A1PPIAPOLBRAB9AL3MBTL1 | |
| SCHEMBL8025559 | 0.87 | MAPT (0.37) | ALDH1A1PPIAPOLBRAB9AKMT2A | |
| SCHEMBL8040243 | 0.77 | PPIA (0.47) | ALDH1A1PPIARAB9AL3MBTL1EPHX2 | |
| SCHEMBL8025492 | 0.76 | PPIA (0.49) | ALDH1A1PPIARAB9AL3MBTL1EPHX2 | |
| SCHEMBL8040256 | 0.76 | ALDH1A1 (0.48) | ALDH1A1PPIAPOLBRAB9AL3MBTL1 | |
| SCHEMBL8037831 | 0.76 | ALDH1A1 (0.48) | ALDH1A1PPIAPOLBRAB9AL3MBTL1 | |
| SCHEMBL8028327 | 0.74 | POLB (0.37) | ALDH1A1POLBRAB9AL3MBTL1PDE4D | |
| SCHEMBL8037861 | 0.72 | PPIA (0.41) | ALDH1A1PPIAPOLBRAB9AL3MBTL1 | |
| SCHEMBL8040252 | 0.72 | ALDH1A1 (0.41) | ALDH1A1POLBKDM4E | |
| SCHEMBL8033883 | 0.71 | PPIA (0.53) | ALDH1A1PPIARAB9AEPHX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |