Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8025492 | 0.99 | PPIA (0.49) | PPIAMAPTGAAALDH1A1HPGD | |
| SCHEMBL8037861 | 0.96 | PPIA (0.41) | PPIAMAPTGAAALDH1A1HPGD | |
| SCHEMBL8037250 | 0.91 | TAS1R3 (0.45) | PPIAMAPTGAAALDH1A1HPGD | |
| SCHEMBL8038220 | 0.86 | PPIA (0.42) | PPIAMAPTGAAALDH1A1KDM4E | |
| SCHEMBL8025559 | 0.82 | MAPT (0.37) | PPIAMAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8035603 | 0.80 | RAB9A (0.40) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8035160 | 0.79 | KMT2A (0.39) | MAPTGAAALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8035162 | 0.77 | ALDH1A1 (0.41) | PPIAALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL8041249 | 0.75 | TAS1R3 (0.35) | ALDH1A1 | |
| SCHEMBL8025495 | 0.74 | KMT2A (0.48) | MAPTALDH1A1SMN1; SMN2RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |