Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | BCL2 | P10415 | 1/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.49 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.49 |
| ▸ | RARB | P10826 | 6/20 | 0.49 |
| ▸ | PTGES | O14684 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL8035864 | 0.91 | LPAR1 (0.50) | SRD5A2LPAR1LPAR5ALOX5TAS2R14 | |
| 4-Methylbenzoic Acid SCHEMBL8025658 | 0.88 | SRD5A2 (0.50) | SRD5A2LPAR1LPAR5TAS2R14ALDH1A1 | |
| SCHEMBL828470 | 0.80 | TAAR1 (0.58) | ALOX5 | |
| Hydrochloric Acid SCHEMBL3660923 | 0.79 | TAAR1 (0.56) | ALOX5 | |
| SCHEMBL7607957 | 0.77 | RARB (0.65) | SRD5A2BCL2RARBMEN1ALDH1A1 | |
| Trimethylammonium SCHEMBL27623056 | 0.73 | EGFR (0.62) | SRD5A2BCL2ALDH1A1MAPT | |
| Terephthalic Acid SCHEMBL1887306 | 0.73 | TSHR (0.62) | SRD5A2ALDH1A1 | |
| Ethane SCHEMBL27330257 | 0.73 | MAPT (0.67) | SRD5A2BCL2MAPT | |
| SCHEMBL7155730 | 0.73 | EGFR (0.72) | SRD5A2MAPTEPHX2NR1H4 | |
| SCHEMBL38562 | 0.73 | EGFR (0.72) | SRD5A2MAPTEPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |