Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3660923 | 0.98 | TAAR1 (0.56) | TAAR1AOC3SIGMAR1CHRM2HTR1A | |
| SCHEMBL11808668 | 0.87 | KCNH2 (0.57) | TAAR1AOC3SIGMAR1CHRM2HTR1A | |
| Benzoic Acid SCHEMBL8035864 | 0.86 | LPAR1 (0.50) | TAAR1ALOX5 | |
| SCHEMBL8896088 | 0.82 | TAAR1 (0.64) | TAAR1AOC3SIGMAR1CHRM2HTR1A | |
| 4-Methylbenzoic Acid SCHEMBL8025658 | 0.80 | SRD5A2 (0.50) | — | |
| SCHEMBL29371723 | 0.78 | TAAR1 (0.61) | TAAR1AOC3SIGMAR1 | |
| SCHEMBL7921601 | 0.77 | TAAR1 (0.52) | TAAR1AOC3SIGMAR1CHRM2HTR1A | |
| SCHEMBL400749 | 0.76 | TSHR (0.54) | TAAR1AOC3SLC6A2SLC6A4ADRA1A | |
| Hydrochloric Acid SCHEMBL7899272 | 0.74 | TSHR (0.52) | TAAR1AOC3SLC6A2SLC6A4ADRA1A | |
| Hydrochloric Acid SCHEMBL10435465 | 0.74 | TAAR1 (0.48) | TAAR1AOC3SIGMAR1HTR1AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612119-A | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents | 西雅图儿童医院（DBA西雅图儿童研究所） | 2019-12-24 | — | — | CN | claimed |
| CN-109859894-A | High-strength aluminum alloy conductor for overhead transmission line | 广西纵览线缆集团有限公司 | 2019-06-07 | — | — | CN | claimed |
| WO-2018148224-A1 | PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS | Seattle Children's Hospital (dba Seattle Children's Research Institute) (US) | 2018-08-16 | — | — | WO | claimed |
| CN-106802684-B | Purple sweet potato pears compound fruit vinegar fermentation monitoring system and its method of work based on MAS | 徐州工程学院 | 2018-05-22 | — | — | CN | claimed |
| CN-106802684-A | Purple potato pears compound fruit vinegar fermentation monitoring system and its method of work based on MAS | 徐州工程学院 | 2017-06-06 | — | — | CN | claimed |
| CN-104672136-B | 1-substituted phenanthryl-N-alkyl (acyl)-6, 7-dimethoxy-1, 2, 3, 4-tetrahydroisoquinoline derivative as well as preparation method and purpose thereof | 沈阳药科大学 | 2017-01-25 | — | — | CN | claimed |
| EP-2961730-A2 | METHOD OF MAKING 1-(ACYLOXY)-ALKYL CARBAMATE COMPOUNDS | XenoPort, Inc. (US) | 2016-01-06 | — | — | EP | claimed |
| CN-104932211-A | Aluminum film water system photoresistance stripping liquid in liquid crystal panel manufacture technology and preparation method thereof | JIANGYIN JIANGHUA MICROELECTRONICS MATERIALS CO LTD | 2015-09-23 | — | — | CN | claimed |
| CN-103965108-B | A kind of method of synthesizing Laudanine | ANTI-DRUG INFORMATION TECHNOLOGY CENTER OF THE MINISTRY OF PUBLIC SECURITY (CN) | 2015-09-23 | — | — | CN | claimed |
| US-20150158809-A9 | METHOD OF MAKING 1-(ACYLOXY)-ALKYL CARBAMATE COMPOUNDS | XENOPORT, INC. (US) | 2015-06-11 | — | — | US | claimed |
| US-6927036-B2 | Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof | XERO PORT, INC. (US) | 2005-08-09 | — | — | US | claimed |
| EP-1507764-A4 | NOVEL ENANTIOMERS OF TETRAHYDROISOQUINOLINE DERIVATIVES AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS | YUN-CHOI HYE-SOOK (KR) | 2005-06-22 | — | — | EP | claimed |
| EP-1507764-A1 | NOVEL ENANTIOMERS OF TETRAHYDROISOQUINOLINE DERIVATIVES AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS | Yun-Choi, Hye-Sook (KR) | 2005-02-23 | — | — | EP | claimed |
| WO-2003095426-A1 | NOVEL ENANTIOMERS OF TETRAHYDROISOQUINOLINE DERIVATIVES AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS | YUN-CHOI HYE-SOOK (KR) | 2003-11-20 | — | — | WO | claimed |
| CN-1231174-A | Medicinal compositions for curing cardio-vascular diseases and benign prostatomegaly | UNIV CHINA PHARMACY (CN) | 1999-10-13 | — | — | CN | claimed |
| US-5684018-A | Acyloxyisopropyl carbamates as prodrugs for amine drugs | MERCK & CO., INC. (US) | 1997-11-04 | — | — | US | claimed |
| WO-1996018605-A1 | ACYLOXYISOPROPYL CARBAMATES AS PRODRUGS FOR AMINE DRUGS | MERCK & CO., INC. (US) | 1996-06-20 | — | — | WO | claimed |
| EP-0130119-B1 | (ACYLOXYALKOXY) CARBONYL DERIVATIVES AS BIOREVERSIBLE PRODRUG MOIETIES FOR PRIMARY AND SECONDARY AMINE FUNCTIONS IN DRUGS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | MERCK & CO. INC. (US) | 1988-11-09 | — | — | EP | claimed |
| US-4760057-A | (Acyloxyalkoxy)carbonyl derivatives as bioreversible prodrug moieties for primary and secondary amine functions in drugs | MERCK & CO., INC. (US) | 1988-07-26 | — | — | US | claimed |
| EP-0130119-A2 | (Acyloxyalkoxy) carbonyl derivatives as bioreversible prodrug moieties for primary and secondary amine functions in drugs, their preparation and pharmaceutical compositions containing said derivatives | MERCK & CO. INC. (US) | 1985-01-02 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150158809-A9 | METHOD OF MAKING 1-(ACYLOXY)-ALKYL CARBAMATE COMPOUNDS | CPS1, CA7, NAAA | TAAR1 1519/4885AOC3 357/4885SIGMAR1 1614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.