Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.59 |
| ▸ | LMNA | P02545 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9447402 | 0.91 | ALDH1A1 (0.54) | ALDH1A1LMNASMN1; SMN2TDP1GAA | |
| SCHEMBL29031409 | 0.89 | ALDH1A1 (0.54) | ALDH1A1LMNASMN1; SMN2TDP1GAA | |
| SCHEMBL29031406 | 0.89 | ALDH1A1 (0.57) | ALDH1A1LMNASMN1; SMN2TDP1GAA | |
| SCHEMBL11765573 | 0.89 | ACHE (0.54) | ALDH1A1LMNASMN1; SMN2TDP1GAA | |
| SCHEMBL29031368 | 0.89 | ALDH1A1 (0.75) | ALDH1A1LMNASMN1; SMN2TDP1GAA | |
| SCHEMBL17833427 | 0.85 | ALDH1A1 (0.61) | ALDH1A1LMNASMN1; SMN2TDP1GAA | |
| SCHEMBL29031398 | 0.84 | ALDH1A1 (0.55) | ALDH1A1LMNASMN1; SMN2TDP1GAA | |
| SCHEMBL29031363 | 0.84 | ALDH1A1 (0.53) | ALDH1A1LMNASMN1; SMN2TDP1GAA | |
| SCHEMBL21889466 | 0.80 | ALDH1A1 (0.55) | ALDH1A1LMNASMN1; SMN2TDP1GAA | |
| SCHEMBL29031388 | 0.80 | ALDH1A1 (0.44) | ALDH1A1LMNASMN1; SMN2TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003336-A | 1,2, 4-triazole-3-amine compound, and preparation method and application thereof | 赣南师范大学 | 2023-04-25 | — | — | CN | disclosed |
| EP-0749957-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5891916-A | ANTINEUROGEGERATIVE AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0749957-A1 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-12-27 | — | — | EP | disclosed |