Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038664 | 0.86 | DRD2 (0.33) | MAOAMAOBDRD2DRD3DRD1 | |
| SCHEMBL5430890 | 0.65 | PBRM1 (0.39) | MAOAMAOBPBRM1DRD2DRD3 | |
| SCHEMBL7493611 | 0.63 | MAOA (0.39) | MAOAMAOBPBRM1DRD2DRD3 | |
| SCHEMBL30917292 | 0.63 | MAOA (0.39) | MAOAMAOBPBRM1DRD2DRD3 | |
| SCHEMBL11313006 | 0.61 | MAOA (0.39) | MAOAMAOBPBRM1DRD2DRD3 | |
| SCHEMBL16685249 | 0.61 | ESR1 (0.36) | MAOAMAOBPBRM1DRD2DRD3 | |
| SCHEMBL1649615 | 0.60 | PBRM1 (0.32) | PBRM1DRD2DRD3DRD1DRD5 | |
| SCHEMBL9508302 | 0.60 | MAOA (0.38) | MAOAMAOBPBRM1DRD2DRD3 | |
| SCHEMBL11603388 | 0.58 | DRD2 (0.42) | MAOAMAOBPBRM1DRD2DRD3 | |
| SCHEMBL3938438 | 0.58 | DRD2 (0.42) | MAOAMAOBPBRM1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661039-B1 | Oxidative hair dyeing method, composition and kit utilizing hydroxyl substituted benzothiazines | BRISTOL MYERS SQUIBB CO (US) | 2000-04-05 | — | — | EP | disclosed |
| EP-0661039-A1 | Oxidative hair dyeing method, composition and kit utilizing hydroxyl substituted benzothiazines | Bristol-Myers Squibb Company (US) | 1995-07-05 | — | — | EP | disclosed |
| US-5374288-A | Oxidative hair dyeing method, composition, and kit utilizing hydroxyl substituted benzothiazines | CLAIROL INCORPORATED (US) | 1994-12-20 | — | — | US | disclosed |