⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetamide SCHEMBL4347036 | 1.00 | — | — | |
| Acetamide SCHEMBL5386560 | 1.00 | LMNA (0.89) | — | |
| Acetamide SCHEMBL28183902 | 0.95 | — | — | |
| Acetamide SCHEMBL27860783 | 0.95 | — | — | |
| Acetamide SCHEMBL20411649 | 0.94 | — | — | |
| Acetamide SCHEMBL2232674 | 0.94 | — | — | |
| Acetamide SCHEMBL20411647 | 0.94 | — | — | |
| Acetamide SCHEMBL3337894 | 0.94 | LMNA (1.00) | — | |
| Acetamide SCHEMBL20411642 | 0.94 | — | — | |
| Acetamide SCHEMBL4953249 | 0.94 | LMNA (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051704-A | REACTING AN AMINO CARBOXYLIC ACID WITH AN ACTIVATED DERIVATIVE SELECTED FROM THE GROUP CONSISTING OF OXALATES AND MALONATES IN THE PRESENCE OF A SUPPORTING SOLVENT AND HEAT TO FORM AN INTERMEDIATE, ADDING A DIAMINE, HEATING | CARNEGIE MELLON UNIVERSITY (US) | 2000-04-18 | — | — | US | disclosed |
| US-6011152-A | REACTING STOICHIOMETRIC AMOUNTS OR MORE OF AN AMINO CARBOXYLIC ACID OR A PROTECTED/ACTIVATED FOR THEREOF WITH AN ACTIVATED DERVATIVE SELECTED FROM THE GROUP CONSISTING OF OXALATES AND MALONATES IN THE PRESENCE OF A SOLVENT AND HEAT | CARNEGIE MELLON UNIVERSITY (US) | 2000-01-04 | — | — | US | disclosed |