Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | CTSC | P53634 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | VHL | P40337 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CPT2 | P23786 | 1/20 | 0.38 |
| ▸ | CPT1A | P50416 | 1/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | MC5R | P33032 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2075088 | 0.91 | VHL (0.49) | GPR119CTSCMEN1KMT2AJAK2 | |
| SCHEMBL2075087 | 0.91 | VHL (0.49) | GPR119CTSCMEN1KMT2AJAK2 | |
| SCHEMBL12383351 | 0.91 | CTSC (0.53) | GPR119CTSC | |
| SCHEMBL8031921 | 0.83 | GPR119 (0.47) | GPR119CTSCMEN1KMT2ANPC1 | |
| SCHEMBL8035777 | 0.82 | MEN1 (0.50) | MEN1KMT2ANPC1USP30LMNA | |
| SCHEMBL7859719 | 0.82 | MEN1 (0.44) | MEN1KMT2ANPC1LMNANPSR1 | |
| SCHEMBL3660022 | 0.80 | GPR119 (0.45) | GPR119CTSCMEN1KMT2AUSP30 | |
| SCHEMBL8028420 | 0.80 | CTSC (0.40) | CTSCMEN1KMT2ANPC1USP30 | |
| SCHEMBL2075366 | 0.78 | VHL (0.54) | CTSCVHL | |
| SCHEMBL2074295 | 0.77 | CTSC (0.59) | CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009074829-A1 | PEPTIDYL NITRILES AND USE THEREOF AS DIPEPTIDYL PEPTIDASE I INHIBITORS | ASTRAZENECA AB (SE) | 2009-06-18 | — | — | WO | disclosed |