Biphenyl

Biphenyl

SCHEMBL8035806

O=C(O)c1ccccc1C(=O)OC(=O)c1ccccc1C(=O)O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.61
ALOX15 P16050 1/20 0.61
CDC25B P30305 1/20 0.57
ATM Q13315 1/20 0.57
MAPT P10636 2/20 0.50
AKR1C3 P42330 1/20 0.48
HNF4A P41235 3/20 0.47
ACMSD Q8TDX5 3/20 0.47
DHFR P00374 1/20 0.47
MCL1 Q07820 1/20 0.47
KDM4E B2RXH2 2/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
HMGB1 P09429 1/20 0.46
HPGD P15428 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA7 P43166 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL713624 0.93 ALDH1A1 (0.70) ALDH1A1ALOX15CDC25BATMMAPT
SCHEMBL248317 0.93 ALDH1A1 (0.70) ALDH1A1ALOX15CDC25BATMMAPT
SCHEMBL29393238 0.93 ALDH1A1 (0.70) ALDH1A1ALOX15CDC25BATMMAPT
SCHEMBL7030042 0.91 ALDH1A1 (0.67) ALDH1A1ALOX15CDC25BATMMAPT
SCHEMBL16585286 0.91 ALDH1A1 (0.67) ALDH1A1ALOX15CDC25BATMMAPT
SCHEMBL3229052 0.89 ALDH1A1 (0.64) ALDH1A1ALOX15CDC25BATMMAPT
SCHEMBL6765311 0.89 ALDH1A1 (0.64) ALDH1A1ALOX15CDC25BATMMAPT
SCHEMBL2205785 0.88 ALDH1A1 (0.52) ALDH1A1ALOX15CDC25BATMMAPT
SCHEMBL2834372 0.87 ALDH1A1 (0.61) ALDH1A1ALOX15CDC25BATMAKR1C3
SCHEMBL6066794 0.87 ALDH1A1 (0.61) ALDH1A1ALOX15CDC25BATMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0444142-B1 POLYQUINOLINE COPOLYMERS HITACHI CHEMICAL CO LTD (JP) 2000-03-29 EP disclosed
US-5017677-A Molding materials, laminates, adhesives, films and fibers COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1991-05-21 US disclosed
WO-1990005754-A1 POLYQUINOLINE COPOLYMERS COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1990-05-31 WO disclosed