SCHEMBL2205785

SCHEMBL2205785

O=C(O)c1ccccc1C(=O)OC(=O)c1ccccc1C(=O)O.O=C(O)c1ccccc1C(=O)OC(=O)c1ccccc1C(=O)O.Oc1ccc(-c2ccc(O)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
ALOX15 P16050 1/20 0.52
CDC25B P30305 1/20 0.50
ATM Q13315 1/20 0.50
MMP3 P08254 1/20 0.50
BCL2L1 Q07817 1/20 0.50
MAPT P10636 2/20 0.49
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
LMNA P02545 1/20 0.48
RAB9A P51151 1/20 0.48
HCAR2 Q8TDS4 1/20 0.47
GAA P10253 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
HNF4A P41235 2/20 0.46
ACMSD Q8TDX5 2/20 0.46
DHFR P00374 1/20 0.46
MCL1 Q07820 1/20 0.46
HSD17B10 Q99714 1/20 0.46
DDX3X O00571 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL8035806 0.88 ALDH1A1 (0.61) ALDH1A1ALOX15CDC25BATMMAPT
SCHEMBL248317 0.86 ALDH1A1 (0.70) ALDH1A1ALOX15CDC25BATMMAPT
SCHEMBL713624 0.86 ALDH1A1 (0.70) ALDH1A1ALOX15CDC25BATMMAPT
SCHEMBL29393238 0.86 ALDH1A1 (0.70) ALDH1A1ALOX15CDC25BATMMAPT
SCHEMBL7030042 0.84 ALDH1A1 (0.67) ALDH1A1ALOX15CDC25BATMMAPT
SCHEMBL16585286 0.84 ALDH1A1 (0.67) ALDH1A1ALOX15CDC25BATMMAPT
SCHEMBL9760944 0.82 ESR1 (0.51) ALDH1A1ALOX15CDC25BMAPTKMT2A
SCHEMBL6765311 0.82 ALDH1A1 (0.64) ALDH1A1ALOX15CDC25BATMMAPT
SCHEMBL3229052 0.82 ALDH1A1 (0.64) ALDH1A1ALOX15CDC25BATMMAPT
Phthalic Acid SCHEMBL9724323 0.82 ALDH1A1 (0.78) ALDH1A1ALOX15MAPTKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220162386-A1 METHOD OF MAKING A BIPHENOL DIANHYDRIDE COMPOSITION, METHOD FOR PURIFICATION OF A BIPHENOL DIANHYDRIDE COMPOSITION, AND POLY(ETHERIMIDES) DERIVED FROM THE BIPHENOL DIANHYDRIDE SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2022-05-26 US disclosed
US-20220073483-A1 METHOD OF MAKING A BIPHENOL DIANHYDRIDE COMPOSITION, METHOD FOR PURIFICATION OF A BIPHENOL DIANHYDRIDE, AND POLY(ETHERIMIDE)S DERIVED FROM THE BIPHENOL DIANHYDRIDE SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2022-03-10 US disclosed
US-7981996-B2 reaction of a diamine such as ortho, meta or para-phenylenediamine with an anhydride like 3- or 4-chlorophthalic anhydride (3-ClPA) in the presence of a solvent (ortho dichlorobenzene) at a temperature above the normal boiling point of the solvent to produce bis/halophthalobisimide/; limited solubility SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-07-19 US disclosed
US-20080119660-A1 reaction of a diamine such as ortho, meta or para-phenylenediamine with an anhydride like 3- or 4-chlorophthalic anhydride (3-ClPA) in the presence of a solvent (ortho dichlorobenzene) at a temperature above the normal boiling point of the solvent to produce bis/halophthalobisimide/; limited solubility GENERAL ELECTRIC COMPANY (US) 2008-05-22 US disclosed
EP-0288974-B1 PROCESS FOR THE PREPARATION OF DIETHER DIPHTHALIC ANHYDRIDES OCCIDENTAL CHEMICAL CORPORATION (US) 1993-09-29 EP disclosed
US-4868316-A Process for the preparation of diether diphthalic anhydrides OCCIDENTAL CHEMICAL CORPORATION (US) 1989-09-19 US disclosed
EP-0288974-A2 Process for the preparation of diether diphthalic anhydrides OCCIDENTAL CHEMICAL CORPORATION (US) 1988-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080119660-A1 reaction of a diamine such as ortho, meta or para-phenylenediamine with an anhydride like 3- or 4-chlorophthalic anhydride (3-ClPA) in the presence of a solvent (ortho dichlorobenzene) at a temperature above the normal boiling point of the solvent to produce bis/halophthalobisimide/; limited solubility DDT, DDC, DDAH1 ALDH1A1 310/4885ALOX15 2718/4885CDC25B 261/4885
US-20220162386-A1 METHOD OF MAKING A BIPHENOL DIANHYDRIDE COMPOSITION, METHOD FOR PURIFICATION OF A BIPHENOL DIANHYDRIDE COMPOSITION, AND POLY(ETHERIMIDES) DERIVED FROM THE BIPHENOL DIANHYDRIDE CA3, FHIT, PPIP5K2 ALDH1A1 4591/4885ALOX15 1888/4885CDC25B 3685/4885
US-20220073483-A1 METHOD OF MAKING A BIPHENOL DIANHYDRIDE COMPOSITION, METHOD FOR PURIFICATION OF A BIPHENOL DIANHYDRIDE, AND POLY(ETHERIMIDE)S DERIVED FROM THE BIPHENOL DIANHYDRIDE CA3, FHIT, PUF60 ALDH1A1 3508/4885ALOX15 1943/4885CDC25B 3790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.