Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12977332 | 0.74 | TSHR (0.57) | TSHRTP53MAPTTDP1L3MBTL1 | |
| SCHEMBL601643 | 0.72 | TSHR (0.59) | TSHRTP53MAPTTDP1PDCD1 | |
| SCHEMBL7691954 | 0.72 | CES1 (0.44) | CES1MAPTKMT2APOLBALDH1A1 | |
| SCHEMBL23777037 | 0.72 | TSHR (0.59) | TSHRTP53MAPTTDP1PDCD1 | |
| SCHEMBL1200862 | 0.72 | TSHR (0.63) | CES1TSHRTP53MAPTTDP1 | |
| SCHEMBL1507630 | 0.71 | CYP2D6 (0.42) | CES1TSHRMAPTKMT2ALMNA | |
| SCHEMBL11474021 | 0.71 | TSHR (0.57) | TSHRTP53MAPTTDP1PDCD1 | |
| SCHEMBL490866 | 0.71 | CES1 (0.47) | CES1TSHRMAPTKMT2APOLB | |
| SCHEMBL11505949 | 0.69 | TSHR (0.55) | TSHRTP53MAPTTDP1L3MBTL1 | |
| SCHEMBL29134108 | 0.69 | TSHR (0.55) | TSHRTP53MAPTPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |