Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | EDNRB | P24530 | 8/20 | 0.41 |
| ▸ | EDNRA | P25101 | 8/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4603935 | 0.80 | PIN1 (0.46) | CES1KCNN4POLBKMT2AMAPT | |
| SCHEMBL28724250 | 0.80 | EDNRB (0.51) | CES1KCNN4CYP1A2CYP2D6EDNRB | |
| SCHEMBL7691954 | 0.78 | CES1 (0.44) | CES1KCNN4CYP1A2CYP2D6EDNRB | |
| SCHEMBL10800116 | 0.77 | CES1 (0.42) | CES1KCNN4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL27315793 | 0.76 | ATM (0.44) | CES1KCNN4CYP1A2CYP2D6EDNRB | |
| SCHEMBL28721298 | 0.74 | EDNRB (0.47) | CES1KCNN4CYP1A2CYP2D6EDNRB | |
| SCHEMBL10512565 | 0.73 | CES1 (0.40) | CES1KCNN4CYP1A2CYP2D6EDNRB | |
| SCHEMBL1507630 | 0.73 | CYP2D6 (0.42) | CES1KCNN4CYP1A2CYP2D6KMT2A | |
| SCHEMBL10884190 | 0.73 | KCNN4 (0.44) | CES1KCNN4CYP1A2CYP2D6KMT2A | |
| SCHEMBL7288198 | 0.72 | CYP1A2 (0.48) | CES1KCNN4CYP1A2CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| US-8598228-B2 | Cinnamic acid ascorbates | MERCK PATENT GMBH (DE) | 2013-12-03 | — | — | US | disclosed |
| US-8268293-B2 | Using compounds which do not themselves exhibit significant UV absorption in the UV-A or UV-B region, but are reactive under use conditions, such as 4-hydroxyphenylpropionic acid, or 2-ethylhexyl 4-hydroxy-3,5-dimethoxycinnamate, or polysiloxanes which contain benzylidenemalonic acid derivatives | MERCK PATENT GMBH (DE) | 2012-09-18 | — | — | US | disclosed |
| US-20120052028-A1 | CINNAMIC ACID ASCORBATES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-03-01 | — | — | US | disclosed |
| US-8106233-B2 | Applying di-2-ethylhexyl 4-hydroxy-3,5-dimethoxy-benzylmalonate; protective action against UV rays, oxidative stress on body cells, counters skin ageing | MERCK PATENT GMBH (DE) | 2012-01-31 | — | — | US | disclosed |
| US-7906684-B2 | Antioxidants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-03-15 | — | — | US | disclosed |
| US-20090246158-A1 | ANTIOXIDANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-10-01 | — | — | US | disclosed |
| US-20090098072-A1 | ANTIOXIDANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-04-16 | — | — | US | disclosed |
| US-20080171004-A1 | Using compounds which do not themselves exhibit significant UV absorption in the UV-A or UV-B region, but are reactive under use conditions, such as 4-hydroxyphenylpropionic acid, or 2-ethylhexyl 4-hydroxy-3,5-dimethoxycinnamate, or polysiloxanes which contain benzylidenemalonic acid derivatives | MERCK PATENT GMBH (DE) | 2008-07-17 | — | — | US | disclosed |
| US-20080152603-A1 | Antioxidants | SUSONITY Commercial GmbH (DE) | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080152603-A1 | Antioxidants | GPX4, GPX1, CAT | CES1 1034/4885KCNN4 2854/4885CYP1A2 250/4885 |
| US-20090246158-A1 | ANTIOXIDANTS | LPO, GPX1, GPX4 | CES1 1806/4885KCNN4 2936/4885CYP1A2 939/4885 |
| US-20090098072-A1 | ANTIOXIDANTS | GPX1, PRDX3, XDH | CES1 757/4885KCNN4 3046/4885CYP1A2 293/4885 |
| US-20080171004-A1 | Using compounds which do not themselves exhibit significant UV absorption in the UV-A or UV-B region, but are reactive under use conditions, such as 4-hydroxyphenylpropionic acid, or 2-ethylhexyl 4-hydroxy-3,5-dimethoxycinnamate, or polysiloxanes which contain benzylidenemalonic acid derivatives | HPD, HAAO, UGT1A6 | CES1 2253/4885KCNN4 4033/4885CYP1A2 325/4885 |
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | LPO, CAT, GPX4 | CES1 993/4885KCNN4 4606/4885CYP1A2 1758/4885 |
| US-20120052028-A1 | CINNAMIC ACID ASCORBATES | PROC, C1S, NISCH | CES1 330/4885KCNN4 4735/4885CYP1A2 232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.