Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11283465 | 0.91 | MEN1 (0.48) | THRBALDH1A1MEN1KMT2AHTT | |
| SCHEMBL15460385 | 0.91 | THRB (0.42) | THRB | |
| SCHEMBL11276252 | 0.91 | MEN1 (0.48) | THRBALDH1A1MEN1KMT2AHTT | |
| SCHEMBL9515106 | 0.90 | THRB (0.40) | THRB | |
| SCHEMBL3833176 | 0.90 | ALDH1A1 (0.46) | THRBALDH1A1MEN1KMT2AHTT | |
| SCHEMBL45482 | 0.89 | THRB (0.36) | THRBALDH1A1 | |
| SCHEMBL23501847 | 0.89 | THRB (0.41) | THRB | |
| SCHEMBL26477509 | 0.89 | THRB (0.41) | THRB | |
| SCHEMBL17460095 | 0.86 | THRB (0.35) | THRBALDH1A1 | |
| SCHEMBL21291961 | 0.86 | THRB (0.35) | THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096692-A | CYLIC KETALS AND ACDTALS HAVING HEAT AND OXIDATION RESISTANCE, ARE FREE FROM CARBOXYLIC ACIDS FORMING DUE TO HYDROLYSIS, LOW IN HYGROSCOPICITY, INEXPENSIVE, GOOD INSULATION AND COMPATIBLE WITH HYDROFLUOROCARBONS; WORKING FLUID REFRIGERANTS | KAO CORPORATION (JP) | 2000-08-01 | — | — | US | disclosed |
| EP-0779289-A1 | SYNTHETIC LUBRICATING OIL | Kao Corporation (JP) | 1997-06-18 | — | — | EP | disclosed |