Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 3/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28471274 | 0.79 | CA2 (0.40) | CA2CA1MAPK1ALDH1A1TSHR | |
| SCHEMBL21811655 | 0.78 | CA2 (0.39) | CA2CA1MAPK1ALDH1A1FAAH | |
| SCHEMBL28325468 | 0.78 | CA2 (0.39) | CA2CA1MAPK1ALDH1A1TSHR | |
| SCHEMBL3023868 | 0.78 | CA2 (0.41) | CA2CA1MAPK1ALDH1A1TSHR | |
| SCHEMBL21811924 | 0.78 | CA2 (0.39) | CA2CA1MAPK1ALDH1A1FAAH | |
| SCHEMBL3814816 | 0.77 | USP2 (0.32) | CA2CA1MAPK1TSHRCYP3A4 | |
| SCHEMBL9839324 | 0.75 | CA2 (0.37) | CA2CA1MAPK1ALDH1A1TSHR | |
| SCHEMBL8679148 | 0.73 | CA2 (0.39) | CA2CA1MAPK1ALDH1A1TSHR | |
| SCHEMBL22844448 | 0.73 | ALDH1A1 (0.40) | CA2CA1ALDH1A1TSHRTDP1 | |
| SCHEMBL5745716 | 0.72 | ALDH1A1 (0.41) | CA2CA1MAPK1ALDH1A1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096692-A | CYLIC KETALS AND ACDTALS HAVING HEAT AND OXIDATION RESISTANCE, ARE FREE FROM CARBOXYLIC ACIDS FORMING DUE TO HYDROLYSIS, LOW IN HYGROSCOPICITY, INEXPENSIVE, GOOD INSULATION AND COMPATIBLE WITH HYDROFLUOROCARBONS; WORKING FLUID REFRIGERANTS | KAO CORPORATION (JP) | 2000-08-01 | — | — | US | disclosed |
| EP-0779289-A1 | SYNTHETIC LUBRICATING OIL | Kao Corporation (JP) | 1997-06-18 | — | — | EP | disclosed |